Results 11 to 20 of about 957,013 (262)
IEEE Transactions on Information Theory, 2010 Significant volumes of knowledge have been accumulated in recent years linking subtle genetic variations to a wide variety of medical disorders from Cystic Fibrosis to mental retardation. Nevertheless, there are still great challenges in applying this knowledge routinely in the clinic, largely due to the relatively tedious and expensive process of DNA ...
Yaniv Erlich +4 more
openaire +3 more sources
Annual Review of Genomics and Human Genetics, 2009 Genotype imputation is now an essential tool in the analysis of genome-wide association scans. This technique allows geneticists to accurately evaluate the evidence for association at genetic markers that are not directly genotyped. Genotype imputation is particularly useful for combining results across studies that rely on different genotyping ...
Yun Li +3 more
openaire +3 more sources
, 2023 The (+) present in all the replicates of the indicated genotype and in none of the other genotypes, (-) absent in at least 1 replicate of the indicated genotype or present in at least 1 replicate of any other genotype. (XLSX)
Adam M. Reitzel (7849394) +2 more
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Mycobacterium tuberculosis Beijing genotype, northern Malawi. [PDF]
, 2005 In a 7-year population-based study in Malawi, we showed that Beijing genotype tuberculosis (TB) increased as a proportion of TB cases. All the Beijing genotype strains were fully drug sensitive.
Drobniewski, Francis A +54 more
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Genotype-specific differences in transcript levels of vitamin C transporter gene.
, 2021 These data were cited from the GTEx Portal on 11/01/2020 (https://gtexportal.org/). In the “GTEx” Portal database, a significant correlation was observed between the genotype of each SNV and the transcript level of SLC23A2 or SLC2A1 in human tissues. The
Koji Hayashi (307068) +21 more
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Performance of genotype imputation for rare variants identified in exons and flanking regions of genes. [PDF]
, 2011 Genotype imputation has the potential to assess human genetic variation at a lower cost than assaying the variants using laboratory techniques. The performance of imputation for rare variants has not been comprehensively studied.
Margaret Gelder Ehm +50 more
core +1 more source
Scrapie prevalence in sheep of susceptible genotype is declining in a population subject to breeding for resistance [PDF]
, 2010 Background Susceptibility of sheep to scrapie infection is known to be modulated by the PrP genotype of the animal. In the Netherlands an ambitious scrapie control programme was started in 1998, based on genetic selection of animals for breeding.
Bossers, A. +18 more
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Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs [PDF]
, 2012 Hepatitis E virus (HEV) is an important but extremely understudied human pathogen. Genotypes 1 and 2 are restricted to humans, whereas genotypes 3 and 4 are zoonotic, infecting both humans and pigs.
Meng, Xiang-Jin +6 more
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