Results 191 to 200 of about 2,304,211 (377)
Advanced Science, EarlyView.ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu +15 more
wiley +1 more source
Diallel analysis of photosynthetic rate and related leaf characters among contrasting genotypes of Lolium perenne [PDF]
, 1969 Deborah J. Wilson, J. P. Cooper
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LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing
Advanced Science, EarlyView.This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang +15 more
wiley +1 more source
MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes
Genetic Epidemiology, 2010 Yun Li +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang +9 more
wiley +1 more source
Opinion 10 Designation of Genotypes for Genera Published with Identical Limits
, 1910 Francis Hemming
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Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy
Science, 2018 D. Chowell +19 more
semanticscholar +1 more source
Advanced Science, EarlyView.This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian +15 more
wiley +1 more source
Opinion 11 The Designation of Genotypes by Latreille, 1810
, 1910 Francis Hemming
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