Results 211 to 220 of about 2,122,472 (401)
A diallel cross of genotypes and genotrophs of Linum [PDF]
A Durrant, H. Tyson
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The study deciphers the landscapes of lineage‐related transcription factors in prostatic adenocarcinoma and neuroendocrine prostate cancer using an innovative approach. These findings, validated across cohorts, highlight TFs' roles in cell development and offer novel therapeutic targets.
Yu Wang+20 more
wiley +1 more source
Influence of Genotype and Environment on Senescence in Peas, Pisum sativum L. [PDF]
G. A. Marx
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The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ
The placenta expresses much higher levels of PPARγ than fetal adipose tissue. Trophoblastic exosomes transport PPARγ into fetal preadipocytes via fetoplacental circulation and thus regulate adipogenic genes distinct from endogenous PPARγ. Compromised placental PPARγ leads to fetal adipogenesis deficiency and intrauterine growth restriction, reversible ...
Xiaofang Luo+17 more
wiley +1 more source
Association of dietary intake of folate, vitamin B6 and B12 and MTHFR genotype with susceptibility of breast cancer [PDF]
De‐Quan Li
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A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang+16 more
wiley +1 more source
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang+16 more
wiley +1 more source
Photoperiod, Temperature and Genotype Interactions Affecting Time of Flowering in Beans, Phaseolus vulgaris L.1 [PDF]
D. S. Padda, H. M. Munger
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Chchd10: A Novel Metabolic Sensor Modulating Adipose Tissue Homeostasis
Chchd10 is a novel regulator of adipose tissue (AT) homeostasis upon excess energy intake. Rapid Chchd10 reduction in response to high‐fat diet induction promotes adipogenesis in subcutaneous AT to store excess energy. On the other hand, sustained Chchd10 reduction protects visceral AT from 4‐HNE‐induced adipocyte dysfunction, attenuating the ...
Xiaoping Wu+11 more
wiley +1 more source