Results 221 to 230 of about 2,304,211 (377)

RAD21L1 Is Sufficient and Effective for Reprogramming Human Sertoli Cells to Phenotypic Spermatogonial Stem Cells Through DNA Methylation and Essential for Male Fertility

Advanced Science, EarlyView.
RAD21L1 is upregulated in human Sertoli cells to be transited to become spermatogonial stem cells by overexpressing DAZ family three genes. RAD21L1 is sufficient and effective for reprogramming Sertoli cells into human spermatogonial stem cells with high safety through DNA methylation.
Caimei He, Yinghong Cui, Wei Chen, Chunyun Li, Zuping He   +4 more
wiley   +1 more source

Genetic polymorphisms of PRL, DGAT1, FSHR, and GH genes and their associations with milk and reproduction traits in Egyptian Buffalo (Bubalus bubalis). [PDF]

BMC Genomics
Zaghloul AR, Khalil MH, Iraqi MM, Amin AMS, El Nagar AG.   +4 more
europepmc   +1 more source

Sofosbuvir and Velpatasvir for HCV Genotype 1, 2, 4, 5, and 6 Infection.

New England Journal of Medicine, 2015
J. Feld, I. Jacobson, C. Hézode, T. Asselah, P. Ruane, N. Gruener, A. Abergel, A. Mangia, Ching‐lung Lai, H. L. Chan, F. Mazzotta, Christophe Moreno, E. Yoshida, S. Shafran, W. Towner, T. Tran, J. McNally, A. Osinusi, E. Svarovskaia, Yanni Zhu, D. Brainard, J. Mchutchison, K. Agarwal, S. Zeuzem   +23 more
semanticscholar   +1 more source

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

Advanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li, Ping Deng, Tengfei Fan, Yuchen Qu, Miduo Tan, Yidan Liang, Peng Gao, Yongchun Peng, Mingke Qin, Sheng Jie, Rongrong Hao, Liting Wang, Lei Zhang, Chunhai Chen, Mindi He, Qinlong Ma, Yan Luo, Li Tian, Jia Xie, Mengyan Chen, Rui Tian, Min Li, Zhengping Yu, Zhou Zhou, Huifeng Pi   +24 more
wiley   +1 more source

Estimating allele frequencies, ancestry proportions and genotype likelihoods in the presence of mapping bias. [PDF]

G3 (Bethesda)
Günther T, Goldberg A, Schraiber JG.
europepmc   +1 more source

Effect of cytoplasmic male sterility and pollen restorer genes on first brood European corn borer resistance among different genotypes of hybrid corn

, 1969
G. R. Pesho
openalex   +1 more source

Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association With Genotype Pattern or Insulin Secretion: The DIETFITS Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2018
C. Gardner, J. Trepanowski, Liana C. Del Gobbo, Michelle E. Hauser, J. Rigdon, J. Ioannidis, M. Desai, A. King   +7 more
semanticscholar   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Deletion of the Voltage-Gated Calcium Channel Gene, Ca_V1.3, Reduces Purkinje Cell Dendritic Complexity Without Altering Cerebellar-Mediated Eyeblink Conditioning. [PDF]

Cerebellum
Klomp A, Pace M, Mehr J, Arrieta MFH, Hayes C, Fleck A, Heiney S, Williams A.   +7 more
europepmc   +1 more source

Environmental and genotype-environmental components of variability II. Heterozygotes [PDF]

, 1966
L Bucio Alanis, J. Hill
openalex   +1 more source