PRDM16 Reduces Cellular Senescence by Upregulating GSTM1
Cellular senescence drives aging and aging‐related organ disorders, yet PRDM16's role remains unexplored. This work uncovers that PRDM16 decreases significantly in aged organs, while its loss accelerates cellular senescence and aging‐related organ injury.
Qian Yuan +7 more
wiley +1 more source
Association of KCNJ11 rs5219 polymorphism with risk of type 2 diabetes and its cardiovascular and renal complications in Noakhali, Bangladesh. [PDF]
Saha P +4 more
europepmc +1 more source
THE B BLOOD GROUP SYSTEM OF CHICKENS. II. THE EFFECTS OF GENOTYPE ON LIVABILITY AND EGG PRODUCTION IN SEVEN COMMERCIAL INBRED LINES [PDF]
W. Elwood Briles, Courtney P. Allen
openalex +1 more source
Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang +4 more
wiley +1 more source
FimA genotype variants of Porphyromonas gingivalis in periodontal health and disease: a preliminary observational study among the UAE population. [PDF]
Yadadi SS +8 more
europepmc +1 more source
The importance of genotype by environment interaction with reference to control populations [PDF]
David F. Bray +2 more
openalex +1 more source
Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding +15 more
wiley +1 more source
Cryptosporidium spp. in wild rodents in the Poyang Lake region, China. [PDF]
Zuo Q +11 more
europepmc +1 more source

