Results 231 to 240 of about 1,614,514 (332)

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

open access: yesAdvanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Association of Gene Polymorphism at Atrial Fibrillation in the Kazakh Population: Case-Control Study. [PDF]

open access: yesGenes (Basel)
Taizhanova D   +5 more
europepmc   +1 more source

PedCheck: a program for identification of genotype incompatibilities in linkage analysis.

open access: yesAmerican Journal of Human Genetics, 1998
J. O’Connell   +2 more
semanticscholar   +1 more source

De Novo Gene Transcription of Connexin Mediates Cytoplasmic Fluid Exchange and Flocking Transitions in Physiological and Cancerous Epithelial Systems

open access: yesAdvanced Science, EarlyView.
EGF‐induced de novo transcription of connexins Cx26 and Cx31 promotes flocking behavior that fluidizes epithelia and enables coordinated collective migration. Connexin‐driven cytoplasmic exchange mechanistically links growth‐factor signaling to invasive dynamics.
Hind Abdo   +18 more
wiley   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

open access: yesAdvanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu   +7 more
wiley   +1 more source

Photochemical Efficiency and Leaf Carbohydrates of <i>Theobroma cacao</i> L. Genotypes Under Different Light Regimes and Cultivation Systems. [PDF]

open access: yesPlants (Basel)
da Vitória J   +12 more
europepmc   +1 more source

Glecaprevir–Pibrentasvir for 8 or 12 Weeks in HCV Genotype 1 or 3 Infection

open access: yesNew England Journal of Medicine, 2018
S. Zeuzem   +37 more
semanticscholar   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

open access: yesAdvanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan   +12 more
wiley   +1 more source

Contributions of selenoproteins to breast cancer etiology and racial disparity. [PDF]

open access: yesCancer Causes Control
Bera S   +12 more
europepmc   +1 more source

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