Results 241 to 250 of about 1,614,514 (332)

A GLUTAMATE CYSTEINE LIGASE Gene StGSH1 Regulated by StERF10 Enhanced Glutathione Accumulation and Adaptation to Low Phosphorus Stress in Potato

Advanced Science, EarlyView.
The StERF10‐StGSH1 module coordinates glutathione (GSH) biosynthesis under low‐phosphorus stress. The low‐phosphate‐induced AP2/ERF transcription factor StERF10 directly activates the transcription of StGSH1 and enhances GSH accumulation. Consequently, GSH scavenges reactive oxygen species and provides sulfur for sulfolipid synthesis, facilitating the ...
Xiaocheng Tian, Mingjun Li, Xiaojia Huang, Markus Wirtz, Xiaohui Zheng, Shilong Fan, Jiang Tian, Shaoqun Liu, Zhonghua Liu, Hongbo Zhao   +9 more
wiley   +1 more source

Association of <i>MMP9</i> and <i>NOS3</i> Polymorphisms with Distinct Clinical Forms of Juvenile Scleroderma and Characteristics of Humoral Immunity. [PDF]

Int J Mol Sci
Osminina M, Podzolkova V, Litvinova M, Geppe N, Chebysheva S, Khachatryan L, Golovanova N, Kostina Y, Lazareva-Batyreva O, Polyanskaya A, Shpitonkova O, Subbotina T, Areian T, Podchernyaeva N.   +13 more
europepmc   +1 more source

Depletion of Sorcs3 Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling Pathways

Advanced Science, EarlyView.
In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang, Xinyu Mao, Yu He, Qingshen Jia, Yiding Zhao, Xiaomeng Dai, Xiaoyan Li, Shengyi Sun, Xiaoyan Sheng, Dan Ding, Yuan Shi, Qian Gao, Ling Shuai   +12 more
wiley   +1 more source

Association of CCL2/CCR2 gene polymorphisms and bladder cancer risk in a hispanic-rich US population. [PDF]

Bladder Cancer
Harmon JF, Santos E, Johnson-Pais TL, Leach RJ, Gelfond J, Mukherjee N, Svatek RS.   +6 more
europepmc   +1 more source

Maintenance of Chronic Fatigue Syndrome (CFS) in Young CFS Patients Is Associated with the 5-HTTLPR and SNP rs25531 A > G Genotype

, 2015
Benedicte Meyer, Chinh Bkrong Nguyen, Aurora Moen, Even Fagermoen, Dag Sulheim, Hilde Nilsen, Vegard Bruun Wyller, Johannes Gjerstad   +7 more
openalex   +2 more sources

Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection.

New England Journal of Medicine, 2015
G. Foster, N. Afdhal, S. Roberts, N. Bräu, E. Gane, S. Pianko, E. Lawitz, A. Thompson, M. Shiffman, C. Cooper, W. Towner, B. Conway, P. Ruane, M. Bourlière, T. Asselah, T. Berg, S. Zeuzem, W. Rosenberg, K. Agarwal, C. Stedman, H. Mo, H. Dvory‐Sobol, Lingling Han, Jing Wang, J. McNally, A. Osinusi, D. Brainard, J. Mchutchison, F. Mazzotta, T. Tran, S. Gordon, K. Patel, N. Reau, A. Mangia, M. Sulkowski   +34 more
semanticscholar   +1 more source

Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins

Advanced Science, EarlyView.
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan, Chong Zhang, Stanislav Ott, Zhiyi Zhang, Christiane Ruse, Sven Dannhäuser, Robert Jacobi, Nadine Ehmann, Divya Sachidanandan, Georg Nagel, Manfred Heckmann, Robert J. Kittel, Alexander Gottschalk, Adam Claridge‐Chang, Shiqiang Gao   +14 more
wiley   +1 more source

Updating the frequency of CCR5Δ32 in Brazil: Descriptive analysis of malaria cases and controls from Acre State, Amazon region. [PDF]

Genet Mol Biol
Ziliotto M, Ellwanger JH, Dombrowski JG, Marinho CRF, Pontillo A, Chies JAB.   +5 more
europepmc   +1 more source

Assessment of genetic variability and character association in okra genotypes for yield and contributing characters

, 2017
Meenakshi Kumari, Shashank Shekhar Solankey, Shirin Akhtar, Pallavi Neha   +3 more
openalex   +2 more sources

Single‐Cell Dissection Reveals Immune Dysregulation After CD5 or CD7‐Directed Chimeric Antigen Receptor T‐Cell Therapy

Advanced Science, EarlyView.
Single‐cell RNA/TCR/BCR sequencing reveals that 5CAR therapy in T‐ALL induces T‐cell exhaustion, reduces EBV‐associated TCRs, lowers TCR/BCR diversity, and increases NK/DC/monocyte activation and function. In contrast, 7CAR therapy reduces multiple pathogen‐associated TCRs, enhances NK cell activation and function, decreases monocyte activation, and ...
Yuechen Luo, Haixiao Zhang, Kaiting Tang, Yiming Wang, Huajiang Dong, Wei Qi, Lingling Shan, Yue Tan, Liping Zhao, Jun Shi, Erlie Jiang, Jing Pan, Xiaoming Feng   +12 more
wiley   +1 more source