Results 301 to 310 of about 2,122,472 (401)

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Advanced Science, EarlyView.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu   +10 more
wiley   +1 more source

Distinct phylogeographic distributions and frequencies of precore and basal core promoter mutations between HBV subgenotype C1 rt269L and rt269I types. [PDF]

Sci Rep
Kim DH, Choi YM, Jang J, Kim Z, Kim BJ.
europepmc   +1 more source

THE MOLECULAR INDIVIDUALITY OF DIFFERENT MOUSE H-2 HISTOCOMPATIBILITY SPECIFICITIES DETERMINED BY SINGLE GENOTYPES

, 1969
D. A. L. Davies
openalex   +1 more source

GENOTYPE AND VARIABILITY IN DAIRY LACTATION RECORDS [PDF]

, 1963
L. D. VanVleck, G.R. Barr
openalex   +1 more source

Autophagy Related 5 Promotes Mitochondrial Fission and Inflammation via HSP90‐HIF‐1α‐Mediated Glycolysis in Kidney Fibrosis

Advanced Science, EarlyView.
When the normal kidney is subjected to injurious stimuli, it can lead to persistent activation of ATG5. The activation of ATG5 promotes HSP90‐HIF‐1α interaction, resulting in stabilization of HIF‐1α and subsequent activation of glycolysis. Consequently, this process contributes to mitochondrial fission and inflammation, ultimately culminating in kidney
Yan Hu, Jinqing Li, Hui Chen, Yingfeng Shi, Xiaoyan Ma, Yi Wang, Xialin Li, Qin Zhong, Yishu Wang, Daofang Jiang, Shougang Zhuang, Na Liu   +11 more
wiley   +1 more source

Genetic diversity of Enterocytozoon bieneusi in 1099 wild animals and 273 imported pastured donkeys in northern China. [PDF]

Parasit Vectors
Wang Z, Cui N, Zhang J, Jiang Z, Song R, Tan W, Yang M, Hornok S, Wang Y.   +8 more
europepmc   +1 more source

Altered Neural Activity in the Mesoaccumbens Pathway Underlies Impaired Social Reward Processing in Shank3‐Deficient Rats

Advanced Science, EarlyView.
This study examines the effects of Shank3 mutation on the mesoaccumbens pathway using a Shank3‐deficient rat model. The findings reveal altered social reward processing in these rats, accompanied by changes in dopaminergic and GABAergic neural activity within the ventral tegmental area (VTA) and dopamine release in the nucleus accumbense (NAc ...
Marie Barbier, Keerthi Thirtamara Rajamani, Shai Netser, Shlomo Wagner, Hala Harony‐Nicolas   +4 more
wiley   +1 more source

Changes in triglyceride-rich lipoprotein particle profiles in response to one-week on a low fat or Mediterranean diet by TCF7L2 rs7903146 genotype: a randomized crossover dietary intervention trial. [PDF]

Genes Nutr
Lai CQ, Gervis JE, Parnell LD, Lichtenstein AH, Ordovas JM.   +4 more
europepmc   +1 more source

Deep Learning‐Enhanced Hand‐Driven Microfluidic Chip for Multiplexed Nucleic Acid Detection Based on RPA/CRISPR

Advanced Science, EarlyView.
Efficient R‐CHIP HR‐HPV Screening System: The R‐CHIP system utilizes the RPA/CRISPR method, a hand‐driven centrifugal microfluidic device, a smartphone micro‐imaging system, and the ResNet‐18 deep‐learning algorithm to simplify the sample detection process, ensure accurate results, and reduce costs.
Tao Xu, Ying Zhang, Shunji Li, Chenxi Dai, Hongguo Wei, Dongjuan Chen, Yunjun Zhao, He Liu, Deliang Li, Peng Chen, Bi‐Feng Liu, Ye Tian   +11 more
wiley   +1 more source

Sequence analysis of the hepatitis D virus across genotypes reveals highly conserved regions amidst evidence of recombination. [PDF]

Virus Evol
Chowdhury S, Jacobsen C, Depledge DP, Wedemeyer H, Sandmann L, Kefalakes H.   +5 more
europepmc   +1 more source