Results 311 to 320 of about 2,122,472 (401)

A Versatile High‐Throughput Single‐Cell Screening Platform for Profiling Antigen‐Specific Long‐Lived B Cells in Blood and Bone Marrow

Advanced Science, EarlyView.
The MoSMAR‐chip platform provides a high‐throughput and cost‐effective tool for identifying and characterizing antigen‐specific antibody‐secreting cells (ASCs) and memory B cells (MBCs) at the single‐cell level. The ASCs from coronavirus disease 2019 (COVID‐19) vaccine‐immunized mice were successfully analyzed, revealing diverse neutralizing antibodies
Tian Zhao, Yuqing Lei, Chang Liu, Dong Zhang, Kaiyi Li, Sisi Shan, Chenyu Li, Zimeng Wei, Yuhan Yang, Ting Zhang, Kai Sun, Haoran Sun, Linqi Zhang, Peng Liu   +13 more
wiley   +1 more source

Genotype × environment interactions [PDF]

Genetics Selection Evolution, 1972
openaire   +4 more sources

Long-Term Outcome of Chronic Hepatitis B-Histological Score and Viral Genotype Are Important Predictors of Hepatocellular Carcinoma. [PDF]

J Viral Hepat
Eilard A, Ringlander J, Andersson ME, Nilsson S, Norkrans G, Lindh M.   +5 more
europepmc   +1 more source

Semaphorin 3E–Plexin D1 Axis Drives Lung Fibrosis through ErbB2‐Mediated Fibroblast Activation

Advanced Science, EarlyView.
TGF‐β1 stimulation in fibroblasts leads to increased Furin expression, Furin‐mediated cleavage of P87‐Sema3E to P61‐Sema3E, which affects fibroblast function through the autocrine pathway, and the P61‐Sema3E‐PlexinD1 axis promotes fibroblast activation, proliferation and migration by affecting ErbB2 phosphorylation, which in turn activates the ErbB2 ...
Zhesong Deng, Jinkun Chen, Ruonan Yang, Yuan Zhan, Shanshan Chen, Jiaheng Zhang, Hao Fu, Yiya Gu, Qian Huang, Jixing Wu, Lianyu Shan, Abdelilah Soussi Gounni, Jungang Xie   +12 more
wiley   +1 more source

Using feedback in pooled experiments augmented with imputation for high genotyping accuracy at reduced cost. [PDF]

G3 (Bethesda)
Clouard C, Nettelblad C.
europepmc   +1 more source

Hierarchical Regulatory Networks Reveal Conserved Drivers of Plant Drought Response at the Cell‐Type Level

Advanced Science, EarlyView.
This study presents a comprehensive multi‐omics framework to uncover cell‐type‐specific regulatory networks in plant drought responses. By integrating transcriptomic, proteomic, and epigenetic data from nearly 30 000 samples, key regulators such as CIPK23 and NLP7 are identified, revealing insights into conserved drought tolerance mechanisms and ...
Moyang Liu, Yuanyuan Xu, Yue Song, Dongying Fan, Junpeng Li, Zhen Zhang, Lujia Wang, Juan He, Cheng Chen, Chao Ma   +9 more
wiley   +1 more source

Genetic Insights Into Early-Onset Type 2 Diabetes Mellitus: The Role of SOST and LRP5 Genotypic Variants in Young Indians. [PDF]

Cureus
Singh J, Singh PK, Amoli R, Kant R, Mirza AA, Naithani M, Saha S.   +6 more
europepmc   +1 more source

INCREASED DIHYDROFOLATE REDUCTASE SYNTHESIS IN DIPLOCOCCUS PNEUMONIAE FOLLOWING TRANSLATABLE ALTERATION OF THE STRUCTURAL GENE. I. GENOTYPE DERIVATION AND RECOMBINATIONAL ANALYSES

, 1969
Francis M. Sirotnak, Sandra L Hachtel
openalex   +2 more sources

MMP9High Neutrophils are Critical Mediators of Neutrophil Extracellular Traps Formation and Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
During a heart attack, neutrophils rapidly activate and differentiate into a specific subset characterized by high levels of MMP9, a tissue‐damaging enzyme, via the SPI1/CST7 pathway. These neutrophils form harmful net‐like structures (Neutrophil extracellular traps, NETs) that exacerbate heart injury.
Shiyu Hu, Feng Zhang, Jingpu Wang, Jian Zhang, Chenguang Li, Yang Lyu, Yiwen Wang, Rong Huang, Yang Gao, Hongbo Yang, Juying Qian, Wenwen Tang, Jiatian Cao, Junbo Ge   +13 more
wiley   +1 more source

Parental kynurenine 3-monooxygenase genotype in mice directs sex-specific behavioral outcomes in offspring. [PDF]

Biol Sex Differ
Milosavljevic S, Piroli MV, Sandago EJ, Piroli GG, Smith HH, Beggiato S, Frizzell N, Pocivavsek A.   +7 more
europepmc   +1 more source