Results 321 to 330 of about 2,122,472 (401)

A Methionine Allocation Nanoregulator for the Suppression of Cancer Stem Cells and Support to the Immune Cells by Epigenetic Regulation

Advanced Science, EarlyView.
A nanoregulator interfering with intratumoral methionine competition is designed to deliver oxaliplatin (IV) prodrugs and anti‐Lat4 small interfering RNA to tumor cells. This Pt (IV)‐crosslinked reduction‐sensitive nanoregulator progressively releases drugs within tumor cells and induces immunogenic cell death.
Boyu Su, Qinjun Chen, Xuwen Li, Mingzhu Fang, Yu Wang, Haolin Song, Haoyu You, Zheng Zhou, Yuxing Wu, Zhenhao Zhao, Yun Chen, Hongrui Fan, Chufeng Li, Chen Jiang, Tao Sun   +14 more
wiley   +1 more source

Genetic Variants in Oxytocinergic System Genes and Their Association with Postpartum Depression Susceptibility. [PDF]

Int J Mol Sci
Ciolac L, Andreescu NI, Farcaș SS, Bernad ES, Tudor A, Nițu DR, Popa DI, Maghiari AL, Craina ML.   +8 more
europepmc   +1 more source

An Insect Salivary Sheath Protein Triggers Plant Resistance to Insects and Pathogens as a Conserved HAMP

Advanced Science, EarlyView.
The salivary sheath protein myosin from SBPH is critical for the formation of the salivary sheath and feeding. However, myosin functions as a HAMP and triggered plant BAK1‐mediated PTI responses, which include the activation of calcium signaling pathways, MAPK phosphorylation, ROS bursts, and cell death, thereby triggering JA pathway.
Liangxuan Qi, Jing Li, Shuai Li, Jing Li, Han Wang, Lei Yang, Xinyang Tan, Zhichang Zhao, Guanghua Luo, Maofeng Jing, Ary A. Hoffmann, Jichao Fang, Rui Ji   +12 more
wiley   +1 more source

Dominance of Vaccine-Specific <i>Chlamydia pecorum ompA</i> Genotypes in Koalas From North-Eastern Australia. [PDF]

Ecol Evol
Sarovich DS, Jelocnik M, Stewart P, Pollak NM, Wong JSF, Kunesh C, Ojiako C, Hanger J, Gillett A, Valenza L, Portas T, Wakeman J, Timms P, Phillips S.   +13 more
europepmc   +1 more source

Genotype-Environment Interactions in Egg Production Stocks of Chickens

, 1969
H.L. MARKS, N.R. Gyles, H.R. Wilson, L.D. Tindell, William A. Johnson, L.J. Dreesen, W.L. Blow, W.F. Krueger, P.B. Siegel   +8 more
openalex   +1 more source

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

Advanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang, Jiahao Cao, Siqi Zhang, Hongli Chen, Xuebing Yu, Xinli Wang, Tianji Wang, Wei Cao, Wengang Dong, Xinsen Lin, Jia Li, Wei Lei, Yafei Feng   +12 more
wiley   +1 more source

Prevalence and genotype analysis of Cryptosporidium spp. in nine species of wild rodents in China. [PDF]

Parasite
Gao ZQ, Wang HT, Li JH, Song YX, Hou QY, Qin SY, Ma H, Zhao Q, Qin Y.   +8 more
europepmc   +1 more source

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

Advanced Science, EarlyView.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen, Jia Liu, Yaoxin Zhang, Changming Shi, Di Zhu, Guoqiang Zhang, Fei Xiao, Lu Zhong, Minyue Zhang, Lai Guan Ng, Honghui Huang, Tingting Lu, Jian Hou   +12 more
wiley   +1 more source

<i>FASN</i>, <i>SCD</i>, and <i>PLAG1</i> Gene Polymorphism and Association with Carcass Traits and Fatty Acid Profile in Hanwoo Cattle. [PDF]

Animals (Basel)
Yu J, Naseem S, Park S, Hur S, Choi Y, Lee T, Li X, Choi S.   +7 more
europepmc   +1 more source

The Effect of Diet on Mortality Attributed to Marek’s Disease Among Leghorn Genotypes

, 1969
F. G. PROUDFOOT, R. John Aitken
openalex   +1 more source