Results 371 to 380 of about 2,122,472 (401)
Some of the next articles are maybe not open access.
Warfarin Pharmacogenetics: To Genotype or Not to Genotype, That Is the Question
Clinical Pharmacology & Therapeutics, 2014Genotype is well recognized to influence the dose of warfarin necessary for therapeutic anticoagulation. Recent randomized controlled trials evaluating the clinical utility of genotype-guided warfarin dosing have produced varying results. We review the design and results of the recent clinical trials, assess the impact of their findings on warfarin ...
Edith A. Nutescu, Larisa H. Cavallari
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Molecular Biotechnology, 2001
This chapter details DNA extraction through polymerase chain reaction (PCR) amplification, gel running, allele assignment, and data management so that the genotyping data produced is suitable for use in linkage analysis programs.
S, Bevan, R S, Houlston
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This chapter details DNA extraction through polymerase chain reaction (PCR) amplification, gel running, allele assignment, and data management so that the genotyping data produced is suitable for use in linkage analysis programs.
S, Bevan, R S, Houlston
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COLONY: a program for parentage and sibship inference from multilocus genotype data
Molecular Ecology Resources, 2010Pedigrees, depicting genealogical relationships between individuals, are important in several research areas. Molecular markers allow inference of pedigrees in wild species where relationship information is impossible to collect by observation.
Owen R. Jones, Jinliang Wang
semanticscholar +1 more source
, 1997
Objective. —To examine more closely the association between apolipoprotein E (APOE) genotype and Alzheimer disease (AD) by age and sex in populations of various ethnic and racial denominations. Data Sources.
L. Farrer +9 more
semanticscholar +1 more source
Objective. —To examine more closely the association between apolipoprotein E (APOE) genotype and Alzheimer disease (AD) by age and sex in populations of various ethnic and racial denominations. Data Sources.
L. Farrer +9 more
semanticscholar +1 more source
Current Protocols in Human Genetics, 2011
AbstractThe identification of genomic loci linked to or associated with human disease has been greatly facilitated by the evolution of genotyping strategies and techniques. The success of these strategies continues to be based upon clear clinical assessment, accurate sample handling, and careful data management, but also increasingly upon experimental ...
Dana C. Crawford, Holli H. Dilks
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AbstractThe identification of genomic loci linked to or associated with human disease has been greatly facilitated by the evolution of genotyping strategies and techniques. The success of these strategies continues to be based upon clear clinical assessment, accurate sample handling, and careful data management, but also increasingly upon experimental ...
Dana C. Crawford, Holli H. Dilks
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Current Protocols in Plant Biology, 2017
AbstractGenotyping‐by‐sequencing (GBS) refers to a suite of related methods that obtain genotype data from samples by using restriction enzyme digestion followed by high‐throughput sequencing. GBS is a refinement of restriction site–associated DNA sequencing (RADseq) methods, with a goal of being able to perform library preparations quickly, cost ...
Jason G. Wallace, Sharon E. Mitchell
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AbstractGenotyping‐by‐sequencing (GBS) refers to a suite of related methods that obtain genotype data from samples by using restriction enzyme digestion followed by high‐throughput sequencing. GBS is a refinement of restriction site–associated DNA sequencing (RADseq) methods, with a goal of being able to perform library preparations quickly, cost ...
Jason G. Wallace, Sharon E. Mitchell
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Neurology, 1996
To the Editor: The editorial by Rosenberg [1] is a superb analysis of the current genotype situation in the field of the hereditary ataxias. Rosenberg is quite right in his comments that the genotype has great importance in clarifying the issue of correlation …
S. H. Subramony, Robert D. Currier
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To the Editor: The editorial by Rosenberg [1] is a superb analysis of the current genotype situation in the field of the hereditary ataxias. Rosenberg is quite right in his comments that the genotype has great importance in clarifying the issue of correlation …
S. H. Subramony, Robert D. Currier
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Journal of the American Medical Association (JAMA), 1997
OBJECTIVE To examine more closely the association between apolipoprotein E (APOE) genotype and Alzheimer disease (AD) by age and sex in populations of various ethnic and racial denominations.
L. Farrer +9 more
semanticscholar +1 more source
OBJECTIVE To examine more closely the association between apolipoprotein E (APOE) genotype and Alzheimer disease (AD) by age and sex in populations of various ethnic and racial denominations.
L. Farrer +9 more
semanticscholar +1 more source
2011
Often in evolutionary genetics research, one needs to analyze polymorphisms in populations for which cost-efficient high-throughput arrays are nonexistent, either because the species is not a model organism or because the populations have been subjected to such specific conditions that their base variation is almost unique.
Martina Bradic +2 more
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Often in evolutionary genetics research, one needs to analyze polymorphisms in populations for which cost-efficient high-throughput arrays are nonexistent, either because the species is not a model organism or because the populations have been subjected to such specific conditions that their base variation is almost unique.
Martina Bradic +2 more
openaire +3 more sources
Electrophoresis, 1999
Within the framework of a pilot project on the analysis of the mouse proteome, we investigated C57BL/6 mice (Mus musculus), a standard inbred strain of the mouse, starting with the analysis of brain, liver and heart proteins. Tissue extraction and the separation of proteins were performed with techniques offering a maximum of resolution.
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Within the framework of a pilot project on the analysis of the mouse proteome, we investigated C57BL/6 mice (Mus musculus), a standard inbred strain of the mouse, starting with the analysis of brain, liver and heart proteins. Tissue extraction and the separation of proteins were performed with techniques offering a maximum of resolution.
openaire +3 more sources