Results 101 to 110 of about 134,396 (261)

Adaptability and Stability Study of Selected Sweet Sorghum Genotypes for Ethanol Production under Different Environments Using AMMI Analysis and GGE Biplots

The Scientific World Journal, 2016
The genotype and environment interaction influences the selection criteria of sorghum (Sorghum bicolor) genotypes. Eight sweet sorghum genotypes were evaluated at five different locations in two growing seasons of 2014.
Justice Kipkorir Rono, Erick Kimutai Cheruiyot, Jacktone Odongo Othira, Virginia Wanjiku Njuguna, Joseph Kinyoro Macharia, James Owuoche, Moses Oyier, Alex Machio Kange   +7 more
doaj   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Stability and adaptability of grain yield in quinoa genotypes in four locations of Iran

Frontiers in Plant Science
The genotype × environment interaction is one of the effective factors in identifying and introducing cultivars with stable grain yield in different environments. There are many statistical methods for estimating genotype × environment interaction, among
Vahid Jokarfard, Babak Rabiei, Ebrahim Souri Laki, Andreas Börner   +3 more
doaj   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Genotype x environment interaction in cassava multi-environment trials via analytic factor.

PLoS ONE
The variability in genetic variance and covariance due to genotype × environment interaction (G×E) can hinder genotype selection accuracy, especially for complex traits.
Juraci Souza Sampaio Filho, Isadora Cristina Martins Oliveira, Maria Marta Pastina, Marcos de Souza Campos, Eder Jorge de Oliveira   +4 more
doaj   +1 more source

Efficiency of Factor Analysis-Based Selection Indices Under Varying Heritability and Trait-Environment Correlations

Agriculture
The main approach for improving multiple traits simultaneously is the selection index. The most widely used selection indices are those based on factor analysis, which overcome statistical limitations such as multicollinearity and the reliance on ...
Wanessa Alves Lima Paiva, Brenda Vieira de Oliveira, Camila Ferreira Azevedo, Ana Carolina Campana Nascimento, Diego Jarquin, Moyses Nascimento   +5 more
doaj   +1 more source

Genotype-environment interaction in personality development:identical twins reared apart

, 1988
The focus of this study is to identify specific genotype-environment (GE) interactions as they contribute to individual differences in personality in later life.
Plomin, R, Pedersen, N L, Bergeman, C S, McClearn, G E, Friberg, L T   +4 more
core   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source