Results 71 to 80 of about 134,396 (261)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
, 2021 Understanding the implication of genotype x environment interaction (GEI) structure is an important consideration in plant breeding programs. The phenotype of an individual is determined by both the genotype and the environment, these two effects are not
Beksisa, Lemi
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
A genotype-environment interaction experiment with bacon pigs
, 1963 SUMMARYA genotype-environment interaction experiment was carried out on a total of 140 pigs. Three genotypes, produced by mating an inbred boar of each of the Large White, Landrace and Wessex Saddleback breeds to Large White sows, were fattened on ...
J. W. B. King
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Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats
Advanced Functional Materials, EarlyView.We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang +18 more
wiley +1 more source
Environment and genotype-environment interaction in maize breeding in Parana, Brazil
Crop Breeding and Applied Biotechnology, 2008 The objectives of this study were: to quantify environmental variation and genotype-environment effects in maize hybrids, within and between two macro-environments in the state of Paraná; and to group the environments according to the hybrid performance ...
Francisco Terasawa Jr. +2 more
doaj
Double‐Interpenetrating Composite Bioink for Multi‐Component 3D Bioprinting and Biofabrication
Advanced Functional Materials, EarlyView.Marine‐polysaccharides‐derived double interpenetrating network hydrogel‐based bioink, combining the attributes of physical and ionic crosslinking, enables room‐temperature bioprinting of mechanically defined structures that can be handled and are cytocompatible.
Fabian Tribukait‐Riemenschneider +1 more
wiley +1 more source
Mechanically Programmable DNA Hydrogel Microparticles for 3D Cellular Systems
Advanced Materials, EarlyView.DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are uptaken into fibroblast spheroids where they are actively remodeled by cellular forces depending on their mechanical properties.
Tobias Walther +9 more
wiley +1 more source
Analysis of Genotype × Environment Interaction for Grain Yield in Chenopodium spp.
Czech Journal of Genetics and Plant Breeding, 2005 Twenty-seven germplasm lines of Chenopodium spp. were grown in four environments and evaluated for genotype × environment interactions and comparisons between 4 stability parameters viz.
A Bhargava, S Shukla, D Ohri
doaj +1 more source
GENOTYPE-ENVIRONMENT INTERACTION IN SPRING WHEAT (Triticuin spp.) [PDF]
, 2014 A Thesis Submitted to the Faculty of Agriculture, Sher-e-Bangla Agricultural University, Dhaka, In partial fulfillment of the requirements for the degree of MASTER OF SCIENCE IN GENETICS AND PLANT BREEDING SEMESTER: January-June, 2014A field ...
ISLAM, MD. SHFUL
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