Results 71 to 80 of about 9,640,965 (252)

Genotype-environment interaction in some rice mutants (Oryza sativa L.) [PDF]

open access: yes, 2013
Stability performance and genotype-environment (G×E) interactions were investigated for yield and yield components of seven rice genotypes at eight cultural soil environments and were measured through linear regression and deviation from regression.
Uddin, M. I.   +5 more
core   +1 more source

Environment and genotype-environment interaction in maize breeding in Parana, Brazil

open access: yesCrop Breeding and Applied Biotechnology, 2008
The objectives of this study were: to quantify environmental variation and genotype-environment effects in maize hybrids, within and between two macro-environments in the state of Paraná; and to group the environments according to the hybrid performance ...
Francisco Terasawa Jr.   +2 more
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Genotype-by-environment effects on grain quality among heat and drought tolerant bread wheat (Triticum aestivum L.) genotypes

open access: yes, 2020
This study determined genotype-by-environment effect on grain quality among heat and drought tolerant bread wheat genotypes to select ideal genotypes for grain quality improvement.
Alfred Odindo (8711790)   +3 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

The Role of Genotype by Environmental Interaction in Plant Breeding [PDF]

open access: yes, 2020
A genotype x environment interaction is a change in the relative performance of a character of two or more genotypes measured into two or more environments.
Begna, Temesgen
core   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini   +9 more
wiley   +1 more source

Genotype x Environment Interaction and Its Stability Measures; Major emphasis in Arabica Coffee: A Review [PDF]

open access: yes, 2021
Understanding the implication of genotype x environment interaction (GEI) structure is an important consideration in plant breeding programs. The phenotype of an individual is determined by both the genotype and the environment, these two effects are not
Beksisa, Lemi
core  

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among US Veterans

open access: yesArthritis Care &Research, EarlyView.
Biomedical research involving US veterans continues to advance health care beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both veteran ...
Austin M. Wheeler   +20 more
wiley   +1 more source

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