Results 11 to 20 of about 26,046,977 (327)
Boceprevir for Untreated Chronic HCV Genotype 1 Infection [PDF]
New England Journal of Medicine, 2011 Peginterferon-ribavirin therapy is the current standard of care for chronic infection with hepatitis C virus (HCV). The rate of sustained virologic response has been below 50% in cases of HCV genotype 1 infection. Boceprevir, a potent oral HCV-protease inhibitor, has been evaluated as an additional treatment in phase 1 and phase 2 studies.We conducted ...
Sprint Investigators
semanticscholar +9 more sources
Predicting Bevirimat resistance of HIV-1 from genotype [PDF]
BMC Bioinformatics, 2010 Background Maturation inhibitors are a new class of antiretroviral drugs. Bevirimat (BVM) was the first substance in this class of inhibitors entering clinical trials.
Hoffmann Daniel +2 more
doaj +3 more sources
Hepatitis E Virus Genotype 1, Cuba
Emerging Infectious Diseases, 2008 nunca llevados a los sitios donde fueron alojados o sacados para pastoreo. Por lo tanto, la única forma de infectar al bebé sería la exposición ambiental. Dado que el bebé no había sido llevado a los sitios de los animales, el patógeno debe haber sido transmitido a la casa por la ropa o la piel del padre o abuelo, que había estado pastoreando a los ...
María de la Caridad Montalvo Villalba +6 more
doaj +3 more sources
Interleukin-1 Genotype in Periodontitis [PDF]
Archivum Immunologiae et Therapiae Experimentalis, 2019 This paper presents the current knowledge concerning the role of polymorphisms of IL1A and IL1B genes in periodontitis. Attention has been paid to the role of IL-1 in the pathogenesis of the disease, and to the significance of a genetic test, investigating the presence of composite two polymorphisms of IL-1 gene, as a risk factor for severe ...
Aniela Brodzikowska +2 more
openaire +2 more sources
Neuregulin 1 Genotype and Schizophrenia [PDF]
Schizophrenia Bulletin, 2007 The neuregulin 1 (NRG1) gene has been the subject of considerable excitement within the psychiatric genetics literature since it was originally identified as a potential susceptibility locus for schizophrenia. Here we provide an update of our first meta-analysis of this association.
Munafò, MR, Attwood, A, Flint, J
openaire +2 more sources
Optimal therapy in genotype 1 patients [PDF]
Liver International, 2009 AbstractMost infections with hepatitis C virus (HCV) fail to resolve spontaneously and progress to chronic hepatitis C. Genotype 1 HCV accounts for most hepatitis C infections in North America, Western Europe, and Japan. Patients infected with HCV genotype 1 are the most resistant to treatment, which results in poor treatment outcomes.
Harald, Farnik +2 more
openaire +2 more sources
Journal of Infection in Developing Countries, 2015 Introduction: The WHO estimates that 180 million people are chronically infected with hepatitis C virus (HCV) throughout the world. Despite the emergence of new therapies, the combination of pegylated interferon and ribavirin remains the accepted ...
Jorge Luis Sandoval-Ramirez +3 more
doaj +1 more source
Biomedicines, 2023 (1) Background: Periodontitis is a chronic multifactorial inflammatory disease associated with dysbiotic plaque biofilms and characterized by progressive destruction of the tooth-supporting apparatus.
Aniela Brodzikowska +2 more
doaj +1 more source
Cost-effectiveness of antiviral therapy in chronic hepatitis C (G1)
Журнал инфектологии, 2016 Updated HCV clinical guidelines placed direct acting agents (DAAs) as the preferable the first line regimens.The objective of the study was PE assessment of HCV therapy among G1 naïve patientsMethods: Analysis is based on data of randomized clinical ...
A. V. Rudakova +3 more
doaj +1 more source
Tailored second line therapy in asthmatic children with the arginine-16 genotype [PDF]
, 2012 The arginine-16 beta-2 receptor genotype confers increased susceptibility to exacerbations in asthmatic children taking regular long acting beta-2 agonists.
Aziz +27 more
core +1 more source