Results 301 to 310 of about 26,046,977 (327)

Drug-resistant genotyping in HIV-1 therapy

The Lancet, 1999
B, Zöllner, H H, Feucht, L, Weitner, A, Adam, R, Laufs   +4 more
  +9 more sources

Geographic distribution of wild poliovirus type 1 genotypes

Virology, 1987
Determination of the patterns of genomic variation among RNA virus isolates is a powerful approach for establishing their epidemiologic interrelationships. The standard technique for such studies, ribonuclease T1 oligonucleotide fingerprinting, can detect similarities only among very closely related isolates.
R, Rico-Hesse, M A, Pallansch, B K, Nottay, O M, Kew   +3 more
openaire   +2 more sources

Primary hyperoxaluria type 1: Genotypic and phenotypic heterogeneity

Journal of Inherited Metabolic Disease, 1994
SummaryPrimary hyperoxaluria type 1 (PH1) is an autosomal recessive disease caused by a deficiency of the liver‐specific peroxisomal enzyme alanine: glyoxylate aminotransferase (AGT). The disease is notable for its extensive heterogeneity at the clinical, biochemical, enzymic and molecular genetic levels.
C J, Danpure, P R, Jennings, P, Fryer, P E, Purdue, J, Allsop   +4 more
openaire   +2 more sources

Genotype Dependent QSAR for HIV-1 Protease Inhibition

Journal of Medicinal Chemistry, 2004
The development of drug-resistant viruses limits the therapeutic success of anti-HIV therapies. Some of these genetic HIV-variants display complex mutational patterns in their pol gene that codes for protease and reverse transcriptase, the most investigated molecular targets for antiretroviral therapy.
Carlo W, Boutton, Hendrik L, De Bondt, Marc R, De Jonge   +2 more
openaire   +2 more sources

HIV-1 Genotyping and Virtual Phenotyping

2012
Drug resistance testing is recommended for the management of patients with HIV-1 infection. Celera ViroSeq™ HIV-1 Genotyping System is the most widely used genotypic HIV drug resistance testing. The assay produces 1,302 nucleotide sequences comprising codons 1–99 of the protease gene and 1–335 of the reverse transcriptase gene.
Fangling Xu, Jianli Dong
openaire   +1 more source

Genotypic Characterization of HIV Type 1 in Jamaica

AIDS Research and Human Retroviruses, 2011
This study seeks to analyze nearly full-length viral genomes for distinct genetic characteristics that are unique to local or regional strains and to identify regions that have high variability or are highly conserved. Nearly full length sequences of seven HIV-1 samples were obtained to ascertain the circulating subtype diversity in the HIV-1 epidemic ...
Marcia E, Roye, Icolyn I, Amarakoon, Cindy-Leigh, Hamilton, Lindsay M, Eyzaguirre, Peter, Figueroa, Jean K, Carr   +5 more
openaire   +2 more sources

Glecaprevir and pibrentasvir yield high response rates in patients with HCV genotype 1-6 without cirrhosis.

Journal of Hepatology, 2017
P. Kwo, F. Poordad, A. Asatryan, Stanley Wang, D. Wyles, T. Hassanein, F. Felizarta, M. Sulkowski, E. Gane, B. Maliakkal, J. S. Overcash, S. Gordon, A. Muir, H. Aguilar, K. Agarwal, G. Dore, Chih‐Wei Lin, Ran Liu, Sandra S. Lovell, T. Ng, J. Kort, F. Mensa   +21 more
semanticscholar   +1 more source

Ledipasvir–Sofosbuvir for 8 Weeks in Non-Cirrhotic Patients with Previously Untreated Genotype 1 HCV Infection ± HIV-1 Co-Infection

Clinical drug investigation, 2018
V. Isakov, N. Gankina, V. Morozov, K. Kersey, Sophia Lu, A. Osinusi, E. Svarovskaia, D. Brainard, R. Salupere, E. Orlova-Morozova, K. Zhdanov   +10 more
semanticscholar   +1 more source

HIV-1 genotyping

Reviews in Medical Microbiology, 2003
openaire   +1 more source

Boceprevir for Chronic HCV Genotype 1 Infection

New England Journal of Medicine, 2011
Alpna R, Limaye, Peter V, Draganov, Roniel, Cabrera   +2 more
openaire   +3 more sources