Results 311 to 320 of about 1,259,951 (349)

Genotypic Characterization of HIV Type 1 in Jamaica

AIDS Research and Human Retroviruses, 2011
This study seeks to analyze nearly full-length viral genomes for distinct genetic characteristics that are unique to local or regional strains and to identify regions that have high variability or are highly conserved. Nearly full length sequences of seven HIV-1 samples were obtained to ascertain the circulating subtype diversity in the HIV-1 epidemic ...
Marcia E, Roye, Icolyn I, Amarakoon, Cindy-Leigh, Hamilton, Lindsay M, Eyzaguirre, Peter, Figueroa, Jean K, Carr   +5 more
openaire   +2 more sources

Treatment of Chronic HCV Genotype 1 Coinfection

Current HIV/AIDS Reports, 2015
Several all-oral direct-acting antiviral (DAA) combination therapies including two fixed-dose combinations (FDCs) have been recently licensed for treatment of hepatitis C virus (HCV) genotype 1 infection. Results of pivotal trials with these new compounds are now also available in human immunodeficiency virus (HIV)/HCV-coinfected patients, highlighting
Christoph, Boesecke, Jürgen K, Rockstroh   +1 more
openaire   +2 more sources

HIV-1 genotypic and phenotypic resistance

Clinics in Laboratory Medicine, 2002
Antiretroviral failure caused by the development of drug resistance in HIV-1 is an increasingly common clinical problem. Two types of resistance assays are available to clinicians. Genotypic assays determine the presence of mutations associated with drug resistance.
openaire   +2 more sources

Neuregulin-1 genotypes and eye movements in schizophrenia

European Archives of Psychiatry and Clinical Neuroscience, 2009
Neuregulin-1 (NRG-1) is a putative susceptibility gene for schizophrenia but the neurocognitive processes that may involve NRG-1 in schizophrenia are unknown. Deficits in antisaccade (AS) and smooth pursuit eye movements (SPEM) are promising endophenotypes, which may be associated with brain dysfunctions underlying the pathophysiology of schizophrenia.
Haraldsson, H.M., Ettinger, U., Magnusdottir, B.B., Ingason, A., Hutton, S.B., Sigmundsson, T., Sigurdsson, E., Petursson, H.   +7 more
openaire   +3 more sources

Evaluation of an in-house genotyping resistance test for HIV-1 drug resistance interpretation and genotyping

Journal of Clinical Virology, 2007
The human immunodeficiency virus type 1 (HIV-1) genotyping resistance test (GRT) has been considered essential for HIV-1 drug resistance monitoring. However, it is not commonly used in some developing countries in Asia and Africa due to its high running cost.This study aims to evaluate a new low-cost in-house GRT for both subtype B and non-B HIV-1.The ...
Yuen, KY, Zheng, BJ, Yam, WC, Li, P, Chen, JHK, Wong, KH, Chan, K, Lam, HY, Lee, SS, Lee, MP, Tsang, DN   +10 more
openaire   +4 more sources

Genotypic analysis of HIV-1 coreceptor usage

2011
The acquired immunodeficiency syndrome (AIDS) is one of the biggest medical challenges in the world today. Its causative pathogen, the human immunodeficiency virus (HIV), is responsible for millions of deaths per year. Although about two dozen antiviral drugs are currently available, progression of the disease can only be delayed but patients cannot be
openaire   +3 more sources

Drug-resistant genotyping in HIV-1 therapy

The Lancet, 1999
B, Zöllner, H H, Feucht, L, Weitner, A, Adam, R, Laufs   +4 more
  +9 more sources

Genotype ✕ Photoperiod and Genotype ✕ Temperature Interactions for Maturity in Maize¹

Crop Science, 1985
A six‐parent diallel of maize (Zea mays L.) was evaluated for total leaf number (TLN), days to tassel initiation (DTI), and to pollen shed (DPS) in 18 diverse field environments and two phytotron environments to determine the contribution of photoperiod and temperature variables to the genotype ✕ environment interaction.
W. K. Russell, C. W. Stuber
openaire   +1 more source

Interactions Between Genotypes of Soybeans and Genotypes of Nodulating Bacteria¹

Agronomy Journal, 1960
SynopsisInteractions were indicated by the chlorosis response of 116 soybean varieties to selected bacterial strains and by a selected group of varieties to 70 bacterial strains. The response of each of 11 varieties to 8 strains was different from that of any other variety. No two of the 8 strains resulted in the same response of all 11 varieties.
Herbert W. Johnson, Ura Mae Means
openaire   +1 more source

HIV-1 Genotyping and Virtual Phenotyping

2012
Drug resistance testing is recommended for the management of patients with HIV-1 infection. Celera ViroSeq™ HIV-1 Genotyping System is the most widely used genotypic HIV drug resistance testing. The assay produces 1,302 nucleotide sequences comprising codons 1–99 of the protease gene and 1–335 of the reverse transcriptase gene.
Fangling Xu, Jianli Dong
openaire   +1 more source