Results 211 to 220 of about 1,197,745 (340)

RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis

Advanced Science, EarlyView.
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao, Chao Ren, Li‐Yu Zheng, Jing‐Yan Li, Wen‐Feng Wu, Yu‐Xuan Li, Li‐Xue Wang, Yu Duan, Lu Wang, Shuang‐Qing Liu, Peng‐Yi He, Peng‐Yue Zhao, Sen Tong, Zhi‐Xuan Li, Tuo Zhang, Meng‐Yao Wu, Shu‐Ting Wei, Ning Dong, Yao Wu, Hui Zhang, Xiao‐Mei Zhu, Zi‐Cheng Zhang, Guo‐Sheng Wu, Zhao‐Fan Xia, Xiao‐Hui Du, Hong‐Jun Kang, Zui Zou, Dao‐Lin Tang, Yong‐Ming Yao   +28 more
wiley   +1 more source

Development of Virus-Like Particles (VLPs) for Hepatitis C Virus genotype 4: a novel approach for vaccine development in Egypt. [PDF]

BMC Biotechnol
Ali AA, Azouz RAM, Hussein NA, El-Shenawy R, Helmy NM, El-Abd YS, Tabll AA.   +6 more
europepmc   +1 more source

893 EARLY VIROLOGICAL RESPONSE RATES IN MONOINFECTED PATIENTS WITH HCV AND COINFECTED WITH HCV/HIV, GENOTYPES 1&4 TREATED WITH PEGINTERFERON alpha 2a AND RIBAVIRIN. OPTIM STUDY

, 2013
Manuel Romero‐Gómez, B. de Cuenca, E. Baeyens, J. García- Samaniego, Javier Salmerón, María del Mar Alonso, J Buenestado, Raquel Muñoz-González, M. Diago, A. García, Carlos Mínguez, Luís Morano, J Giron, Juan Sánchez-Hernández, Juan González‐García, R. Solà   +15 more
openalex   +2 more sources

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Introduction of dengue virus 4 (DENV-4) genotype I into Brazil from Asia? [PDF]

PLoS Neglected Tropical Diseases, 2009
Fernando Lucas de Melo, Camila Malta Romano, Paolo Marinho de Andrade Zanotto   +2 more
doaj   +1 more source

Evaluation of pandemic potential of the genotype 4 (G4) swine influenza virus using <i>ex vivo</i> and <i>in vitro</i> cultures of the human respiratory tract. [PDF]

J Gen Virol
Chan JCM, Ching RHH, Kock HHM, Long T, Nicholls JM, Peiris JSM, Hui KPY, Chan MCW.   +7 more
europepmc   +1 more source

984 EMERGING HEPATITIS E GENOTYPE 4 INFECTION IN FRANCE

, 2013
Asma Jeblaoui, S. Haïm-Boukobza, Anthony Pause, Camélia Mokhtari, É. Nicand, A.M. Roque-Afonso   +5 more
openalex   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Characterisation of a Japanese Encephalitis virus genotype 4 isolate from the 2022 Australian outbreak. [PDF]

Npj Viruses
Nguyen W, Gyawali N, Stewart R, Tang B, Cox AL, Yan K, Larcher T, Bishop CR, Wood N, Devine GJ, Suhrbier A, Rawle DJ.   +11 more
europepmc   +1 more source