Results 211 to 220 of about 14,985,405 (291)

Multi-environment evaluations reveal that peanut (<i>Arachis hypogaea</i> L.) quality traits are equally determined by genotype and environment. [PDF]

Front Plant Sci
Jiang X, Zhao J, Xu J, Yin D, Xie H, Chen N, Pan L, Yin X, Ma J, Zhao X, Chi X.   +10 more
europepmc   +1 more source

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

Advanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang, Wenzhuo Yang, Wenting Cheng, Jing Zuo, Lin Pan, Sheng Zhong, Ren Geng, Yao Zhao, Zijian Chen, Canhua Huang, Yang Bai, Liyan Zhao, Yunqian Li   +12 more
wiley   +1 more source

Deconstructing empirical fitness seascapes across scales of granularity. [PDF]

G3 (Bethesda)
Manivannan SN, Ogbunugafor CB.
europepmc   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

Stability of grain and fodder yields in extra-early cowpea genotypes in Southeastern Niger. [PDF]

PLoS One
Abdou S, Iro Sodo AM.
europepmc   +1 more source

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

Advanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin, Yujia Shi, Ruoyu Zhang, Yong Xiang, Jinghong Qiu, Pak‐Chung Sham, Hon‐Cheong So   +6 more
wiley   +1 more source

Associations of <i>ASIC2</i>, <i>IKZF3</i>, and <i>GSDMB</i> Variants with Gestational Diabetes Mellitus and Their Interactions with Environmental Exposures Among Chinese Women. [PDF]

Biomolecules
Wang S, Huang X, Shen X, Zhang Y, Tao L, Zhou Y, Yu H, Wang X.   +7 more
europepmc   +1 more source

Infant pathways to externalizing behavior: evidence of Genotype x Environment interaction. [PDF]

Child Dev, 2010
Leve LD, Kerr DC, Shaw D, Ge X, Neiderhiser JM, Scaramella LV, Reid JB, Conger R, Reiss D.   +8 more
europepmc   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

<i>COMT</i> rs4680 polymorphism modulates openness to experience in women with alcohol use disorder. [PDF]

Postep Psychiatr Neurol
Zdunek G, Recław R, Chmielowiec K, Suchanecka A, Grywalska E, Chmielowiec J, Larysz D, Grzywacz A.   +7 more
europepmc   +1 more source