Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao +19 more
wiley +1 more source
Omentin-1 Val109Asp polymorphism and increased coronary artery disease risk in smokers with type 2 diabetes. [PDF]
Yu D +9 more
europepmc +1 more source
From Defense Executor to Engineering Target: Harnessing Lignin for Crop Resistance
Lignin serves as both a physical and chemical executor of broad‐spectrum plant immunity. This review systematically summarizes classical and recent advances in lignin‐mediated immunity, outlines the multifaceted regulatory modules controlling lignification under biotic stress, discusses key physiological and biochemical mechanisms behind lignin‐based ...
Yanwen Yu +6 more
wiley +1 more source
Development of disease-resistant, stable high-yielding, and high-quality rice variety "Yunjing-60" through double-cropping acceleration and intensive multi-environment selection in mid-altitude regions. [PDF]
Kou S +8 more
europepmc +1 more source
Infant pathways to externalizing behavior: evidence of Genotype x Environment interaction. [PDF]
Leve LD +8 more
europepmc +1 more source
Genotype X Environment Interaction and Stability Analysis in Mustard
Abdul Rashid +4 more
openaire +1 more source
The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton
Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang +32 more
wiley +1 more source
Genotype × environment interaction and stability of grain micronutrients in wheat under organic and conventional systems: AMMI and GGE analysis. [PDF]
Motawei MI +4 more
europepmc +1 more source
Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami +15 more
wiley +1 more source
Genotype by environment interaction and yield stability analysis of durum wheat (Triticum turgidum var. durum) varieties using AMMI and GGE biplot analysis in Amahara Region, Northwest Ethiopia. [PDF]
Eskezia A +4 more
europepmc +1 more source

