Genetic architecture of angular leaf spot resistance in cultivated strawberry shaped by epistasis and genotype-by-environment interactions. [PDF]
Torgeman S +6 more
europepmc +1 more source
Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau +22 more
wiley +1 more source
Dopaminergic gene-epigenetic interactions and impulsivity traits in elite combat sport athletes. [PDF]
Recław R +4 more
europepmc +1 more source
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas +13 more
wiley +1 more source
<i>CDKN2A/2B</i> gene variants and gene-environment interactions increase the risk of gestational diabetes mellitus in Chinese women. [PDF]
Zhang Y, Yang R, Wang X, Yu H.
europepmc +1 more source
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang +10 more
wiley +1 more source
Study of Genotype X Environment Interaction in Alfalfa Forage Yield
The response of alfalfa (Medicago sativa L.) forage yield to eight Alberta test sites was studied for the 1990 and 1991 production years. Cluster analysis was used to group locations and cultivars.
Acharya, S N +3 more
core
Plant and aphid genotypes modulate legume rhizobium-induced defense against aphids. [PDF]
Pandharikar G +5 more
europepmc +1 more source
The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source
Randomization across breeding cohorts improves the accuracy of conventional and genomic selection. [PDF]
Ackerman A, Rutkoski J.
europepmc +1 more source

