Results 41 to 50 of about 243,271 (342)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
The impact of imprecisely measured covariates on estimating gene-environment interactions [PDF]
, 2006 BACKGROUND The effects of measurement error in epidemiological exposures and confounders on estimated effects of exposure are well described, but the effects on estimates for gene-environment interactions has received rather less attention.
Cade, J.E. +2 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Pesquisa Agropecuária Brasileira, 2022 The objective of this work was to decompose the variations of the genotype × environment interaction through fixed multivariate models, as well as to understand the genetic variations through mixed models, for the estimation and prediction of the genetic
Kassiana Kehl +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The genetical examination of 'Grasslands Ariki' ryegrass Lolium ((multiflorum x perenne) x perenne) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Plant Science [PDF]
, 1970 'Grasslands Ariki' ryegrass - Lolium [(multiflorum x perenne) x perenne] - has been established in New Zealand as a successful pasture variety. While some genetic parameters were determined during its breeding programme, no diallel cross analyses have ...
Sedcole, John Richard
core
Genotype X Environment Interaction of Food Barley
Ecoprint: An International Journal of Ecology, 2015 The objective of this experiment was to estimate the magnitude of genotype X environment interaction on grain yield and yield related traits. Twelve varieties of food barley were included in the study planted in randomized complete block design with three replications. The ANOVA of combined and individual location revealed significant differences among
openaire +2 more sources
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
AMMI & GGE BIPLOT: uma análise comparativa da avaliação de locais de teste de genótipos de arroz. [PDF]
, 2014 Ensaios de Valor de Cultivo e Uso (VCU) são de grande importância no melhoramento de plantas. A análise desses experimentos é comumente realizada utilizando-se diversas ferramentas estatísticas.
BRANQUINHO, R. G. +7 more
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GENOTYPE x ENVIRONMENT INTERACTION WITH ISOGENIC LINES OF DROSOPHILA MELANOGASTER [PDF]
Genetics, 1963 Two experiments which exploit some of the peculiar genetic properties of Drosophila melanogaster were conducted to study the nature of the interaction of genotype x environment. All possible crosses were made among four isogenic lines, each representing a different mass mated stock.
openaire +2 more sources