Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun +7 more
wiley +1 more source
Hypothetical Pneumocystis jirovecii Transmission from Immunocompetent Carriers to Infant
Philippe Hauser +12 more
doaj +1 more source
Assessment of salinity tolerance in onion (<i>Allium cepa</i> L.) genotypes at germination stage through morphological traits and multivariate analysis. [PDF]
Kasar S +10 more
europepmc +1 more source
Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai +13 more
wiley +1 more source
Seed yield and nutrition in slow-wilting soybean breeding lines as influenced by irrigated and non-irrigated conditions in the Midsouth USA. [PDF]
Bellaloui N +3 more
europepmc +1 more source
Is it necessary to delay antiviral therapy for 3-6 months to anticipate HBeAg seroconversion in patients with HBeAg-positive chronic hepatitis B in endemic areas of HBV genotype C? [PDF]
Byung‐Cheol Song +8 more
openalex +1 more source
Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon +10 more
wiley +1 more source
Breeding climate-resilient wheat for Nepalese agricultural system under diverse abiotic stresses using an integrated AMMI, GGE and stress tolerance indices. [PDF]
Bhandari R +5 more
europepmc +1 more source

