Results 281 to 290 of about 1,309,818 (329)

Genotyping [PDF]

, 2020
openaire   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Predicting enviromically adapted varieties with big data. [PDF]

Genome Biol
Gogna A, Kamali B, Wimmer V, Schmidt RH, Rezaei EE, Eckhoff WM, Reif JC, Zhao Y.   +7 more
europepmc   +1 more source

Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques

Advanced Science, EarlyView.
Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang, Ying Hu, Yang Teng, Jiwei Qi, Yangzhen Ciren, Lin Zhang, Qiao Du, Wencai Xu, Liang Zhou, Zhenxin Fan, Jinchuan Xing, Ming Li, Jing Li   +12 more
wiley   +1 more source

Physiological and Morphological Response Mechanisms of <i>Theobroma cacao</i> L. Rootstocks Under Flooding and Evaluation of Their Adaptability. [PDF]

Plants (Basel)
Pinto MLPB, Oliveira VS, Crasque J, Cerri Neto B, Ferreira TR, Souza CAS, Falqueto AR, Souza TC, Machado Filho JA, Arantes LO, Dias CDS, de Santana EN, Tesch Kuhlcamp K, Dousseau-Arantes S.   +13 more
europepmc   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Synergism of IP3R and Parkin mutants identifies mitochondrial stress as an early feature of Parkinson's disease.

Dis Model Mech
Dileep M, Sharma A, Kasturacharya N, Nizami SK, Manjila S, Bhan A, Hasan G.   +6 more
europepmc   +1 more source

Agromorphological Characterization and Variability Among Maize Hybrids in the Mid-Hills of Far-West Nepal. [PDF]

Scientifica (Cairo)
Chandra Bhatta R, Risal A, Shrestha A, Thapa S, Tripathi MP.   +4 more
europepmc   +1 more source

Domestication of Tartary Buckwheat Shaped a Regulatory Module for Seedling Salt Tolerance by Targeting the Magnesium Transporter Gene FtMGT2

Advanced Science, EarlyView.
Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu, Yuqi He, Wenfeng Weng, Zebin Liu, Yuanfen Gao, Yaliang Shi, Wei Li, Dili Lai, Mengyu Zhao, Rintu Jha, Hui Zhao, Guangsheng Li, Chaonan Guan, Shuai Shao, Jingjun Ruan, Sun Hee Woo, Yinan Ouyang, Muriel Quinet, Milen I. Georgiev, Alisdair R. Fernie, Congcong Hou, Kaixuan Zhang, Xu Liu, Meiliang Zhou   +23 more
wiley   +1 more source

Structural Insights into the Interaction Between a Core-Fucosylated Foodborne Hexasaccharide (H₂N₂F₂) and Human Norovirus P Proteins. [PDF]

Viruses
Zhang Z, Wang Y, Xu J, Liu F, Li S, Cox JT, Xue L, Liu D.   +7 more
europepmc   +1 more source