Results 161 to 170 of about 141,362 (266)

Modern elite winter wheat cultivars use two physiological pathways to achieve yield stability. [PDF]

J Exp Bot
Wang TC, Liu LY, Weiß K, Chen TW.
europepmc   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

Biofilm-Forming Methicillin-Resistant Staphylococcus aureus: A Comprehensive Phenotypic and Genotypic Review. [PDF]

Cureus
Bhujugade SR, Patil HV, Patil SR.
europepmc   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Association of TIMP2 Gene Variants With Development of Diabetic Retinopathy. [PDF]

In Vivo
Huang CT, Chien HW, Wang K, Su SC, Ting CH, Yang SF, Liao MY.   +6 more
europepmc   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

Improving genomic prediction in wheat with random regression models with genotype-specific phenology-driven environmental covariates. [PDF]

Plant Genome
Dhakal R, Sniadower G, Silva P, Lado B, Sandro P, Rebollo I, Quincke M, Dawson JC, Gutiérrez L, González Barrios P.   +9 more
europepmc   +1 more source

GENOTYPE-ENVIRONMENT INTERACTION AND GENOTYPIC STABILITY FOR SOME EGYPTIAN COTTON GENOTYPES

Egyptian Journal of Agricultural Research, 1998
SAMER A. EL-SHAARAWY, YAHUA M. ATTA, MOHAMED A. A. RAAFAT, ABDEL-MOTY ZEINA   +3 more
openaire   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Selecting stable rice mutants with linear mixed models (LMM) and stability indexes. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Sharifi P, Ebadi AA, Hallajian MT, Aminpanah H.   +3 more
europepmc   +1 more source