Results 91 to 100 of about 55,163 (272)

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Distribution of genetic diversity in wild European populations of prickly lettuce (Lactuca serriola): implications for plant genetic resources management [PDF]

, 2010
Genetic variation in Lactuca serriola, the closest wild relative of cultivated lettuce, was studied across Europe from the Czech Republic to the United Kingdom, using three molecular marker systems, simple sequence repeat (SSR, microsatellites), AFLP and
Dehmer, K.J., Hintum, T.J.L., van, Linden, C.G., van der, Sretenovic Rajicic, T., Treuren, R., van, Wiel, C.C.M., van de   +5 more
core   +2 more sources

Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly

Advanced Science, EarlyView.
Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao, Juntao Hu, Juan Du, Shaokun Guo, Youming Hou, Zhihong Li   +5 more
wiley   +1 more source

Genetic Variability in Distinct Genotypes of Forage Pearl Millet (Pennisetum glaucum (L.) R. Br.) for Forage Yield and Forage Yield Attributing Traits

International Journal of Economic Plants
The experiment was conducted during kharif (July–October, 2023) at Centre for Forage Research, S. D. Agricultural University, Sardarkrushinagar, Gujarat, India to study to appraise genetic variability in pearl millet genotypes for fodder yield and ...
Ritu Sharma, Y. A. Viradiya, A. R. Donga, T. A. Parsaniya, Jogender Beniwal, Patel Parth Jivan   +5 more
doaj   +1 more source

Genetic variability, correlations and path coefficient analysis of components of seed yield in cowpea (Vigna unguiculata) [PDF]

, 1995
Twenty-six varieties of cowpea (Vigna unguiculata L Walp,) were evaluated in the field to study genetic variability, inter-character relationships as well as the path analysis oj components oj seed yield. Seed yield was the most variable character with
O. J., Ariyo
core  

Assessment of genetic variability and character association for grain yield and its component traits in bread wheat (Triticum aestivum L.) [PDF]

, 2018
A study was conducted for estimating genetic variability and characters association for eleven yield components using 169 genotypes (13 parents, 78 F1 and 78 F2) of bread wheat through half-diallel mating design during rabi season 2012-13 and 2013-14 ...
Kumar, Pradeep, Nagar, Satnam Singh, Singh, Gyanendra, Tyagi, B. S., Vishwakarma, S.R.   +4 more
core   +2 more sources

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

Potential inbreeding in a small population of a mass flowering species, Xanthorrhoea johnsonii (Xanthorrhoaceae): is your mother my father? [PDF]

, 2012
Xanthorrhoea johnsonii is a long lived slow growing perennial understorey species, that produces a large quantity of passively dispersed seed every 3-5 years. Reproductive maturity is not reached until 20-30 years of age.
King, Rachel, Zalucki, Jacinta M.
core   +2 more sources

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Genetic analysis and qtl mapping of agro-morphological traits in lowland rice (Oryza sativa L.) under drought conditions [PDF]

, 2016
The present study was undertaken to evaluate lowland rice genetic variability associated with agro-morphological traits under drought condition. A set of 250 recombinant inbred lines (RILs) from the cross between rice parental cultivarIR64 (sensitive to ...
Audebert, Alain, Hema, Drissa, Kam, Honore, Konate, Abdourasmane K., Sangaré, Jean Rodrigue, Sanni, Ambaliou, Zongo, Adama   +6 more
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