Results 121 to 130 of about 55,687 (266)

Studies on genetic variability correlation and path analysis in upland cotton

open access: yesElectronic Journal of Plant Breeding, 2020
The research work for studying genetic variability, heritability and genetic advance as well as correlation and path coefficient analysis for 13 traits with sixty seven genotypes of upland cotton was carried out during winter 2017 at Cotton Research ...
M. Gnanasekaran, K. Thiyagu and M. Gunasekaran
doaj   +1 more source

Measuring Plant Genetic Diversity Using Inter-Simple Sequence Repeats (ISSRS) [PDF]

open access: yes, 2007
Simple sequence repeats (SSRs) have great utility as they are conserved and present in all eukaryotic genomes. Here we report the use of a simple PCR with fluorescently-labelled primers to amplify inter-SSR markers (ISSRs) for diversity assessments.
Iannetta, Pietro
core  

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

open access: yesAdvanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu   +11 more
wiley   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

Genetic control of plasticity of oil yield for combined abiotic stresses using a joint approach of crop modeling and genome-wide association

open access: yes, 2017
Understanding the genetic basis of phenotypic plasticity is crucial for predicting and managing climate change effects on wild plants and crops.
André, Thierry   +16 more
core   +4 more sources

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

open access: yesAdvanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao   +7 more
wiley   +1 more source

Assessing genetic variability and heritability in the F4 population of mutant Bioguma and Gando Keta local Indonesian sorghum [Sorghum bicolor (L.) Moench]

open access: yesCzech Journal of Genetics and Plant Breeding
This study examined the genetic variability, heritability, and genetic advance in the F4 generation of sorghum to enhance grain productivity. The study was conducted at Citayam Research Station, Depok Indonesia (March-September 2023), and evaluated 102 ...
Endang Lestari   +8 more
doaj   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

open access: yesAdvanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen   +14 more
wiley   +1 more source

A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection

open access: yesAdvanced Science, EarlyView.
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang   +8 more
wiley   +1 more source

Genotypic Variability in Root Morphological Traits in Canola (Brassica napus L.) at the Seedling Stage

open access: yesCrops
Canola (Brassica napus L.) is a vital oilseed crop, but its sustainable production is increasingly challenged by climate change. Characterizing genotypic variation in root morphological traits in canola provides a basis for breeding new varieties with ...
Yongkang Peng   +3 more
doaj   +1 more source

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