BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang +9 more
wiley +1 more source
Frequency of Polymorphisms in <i>SLC47A1</i> (rs2252281 and rs2289669) and <i>SLC47A2</i> (rs34834489 and rs12943590) and the Influence of <i>SLC22A1</i> (rs72552763 and rs622342) on HbA1c Levels in Mexican-Mestizo Patients with DMT2 Treated with Metformin Monotherapy. [PDF]
Gómez-Hernández MA +5 more
europepmc +1 more source
PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang +13 more
wiley +1 more source
Estimating and testing the effect of allelic recombination on the correlation between genotypic relatives [PDF]
Ikewelugo Cyprian Anene Oyeka +2 more
openalex +1 more source
CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan +21 more
wiley +1 more source
Mainly high phenotypic stability of black spruce clones for growth and wood traits in contrasted environments within the current breeding zones and multitrait selection in Québec's seed and breeding zones. [PDF]
Desponts M +3 more
europepmc +1 more source
Phenotypic and genotypic correlations between soybean agronomic traits and path analysis
Beliza Queiroz Vieira Machado +8 more
openalex +1 more source
VARIABILITY IN 19 VARIETAL WHEAT BLENDS AND GENOTYPIC AND PHENOTYPIC CORRELATIONS FOR MORPHOLOGICAL AND YIELD CHARACTERS [PDF]
F. F. Saad +3 more
openalex +1 more source
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang +9 more
wiley +1 more source

