Results 131 to 140 of about 456,399 (317)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Molecular Characterization of the Chicken Parvovirus Based on VP1 Gene Circulating in Brazilian Chicken Flocks

Microorganisms
Parvovirus infection affects several animal species, especially young animals. In birds, parvovirus infection has been described in Muscovy ducks, turkeys, and chickens, all of which had enteric diseases characterized by diarrhea.
Luis F. N. Nuñez, Silvana H. Santander-Parra, Claudete S. Astolfi-Ferreira, Anthony Loor-Giler, Antonio J. P. Ferreira   +4 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Genotyping of Toxoplasma gondii in domestic animals from Campeche, México, reveals virulent genotypes and a recombinant ROP5 allele

Parasitology
Toxoplasma gondii has at least 318 genotypes distributed worldwide, and tropical regions usually have greater genetic diversity. Campeche is a state located in the southeastern region of México and has favourable climate conditions for the replication ...
Claudia Patricia Rico-Torres, Luis Fernando Valenzuela-Moreno, Elvira Robles-González, Alvar Alonzo Cruz-Tamayo, Miguel Huchin-Cab, Jonathan Pérez-Flores, Lizbeth Xicoténcatl-García, Héctor Luna-Pastén, Luz Belinda Ortiz-Alegría, Irma Cañedo-Solares, Carlos Cedillo-Peláez, Fernando García-Lacy, Heriberto Caballero-Ortega   +12 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Thalassemia: genotypes and phenotypes

Annals of Hematology, 1991
The large degree of phenotypic heterogeneity of thalassemia can now be related to the underlying genomic defects. This information has accumulated rapidly over the last years through the recent advances in molecular technology. The list of main types of thalassemia (alpha or beta) that can be differentiated includes several gene deletions (complete or ...
openaire   +5 more sources

Noninvasive fetal RHD genotyping to guide targeted anti-D prophylaxis–an external quality assessment workshop

, 2019
Background and Objectives: Fetal RHD genotyping of cell-free fetal DNA from RhD-negative pregnant women can be used to guide targeted antenatal and postnatal anti-D prophylaxis for the prevention of RhD immunization.
Noninvasive Fetal RHD Genotyping EQA2017 Working Group, Clausen, Frederik Banch, Barrett, Angela Natalie   +2 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Frequency and Sequence Analysis of Echinococcus granulosus Sensu Lato Isolated From Buffaloes in Northern Iran

Veterinary Medicine and Science
Background Echinococcus granulosus sensu lato is one of the most important zoonotic parasites in many regions of the world. Cystic echinococcosis (CE) is a major economic and public health challenge in Iran.
Fariborz Ghanbari, Keyhan Ashrafi, Majid Fasihi Harandi, Somayeh Abbaszadeh, Asieh Ashouri, Elham Hajialilo, Meysam Sharifdini   +6 more
doaj   +1 more source

Genotyping-by-Sequencing (GBS) of large amphibian genomes: a comparative study of two non-model species endemic to Italy: supplementary material

, 2019
Next Generation Sequencing (NGS) and related technologies have revolutionized the field of conservation and population genetics, providing novel tools and the capacity to discover thousands of new Single Nucleotide Polymorphisms (SNPs) for the analysis ...
David R. Vieites (546308), Vincenzo Buono (6017185), Daniele Macale (6017183), Nadav Pezaro (6017191), Ettore Randi (42572), Leonardo Vignoli (6017181), Aritz Ruiz-González (645630), Francesca Davoli (6017188), Valentina Rovelli (6017179)   +8 more
core   +1 more source