A combined risk model shows viability for personalized breast cancer risk assessment in the Indonesian population: A case/control study. [PDF]
Rabbani B+23 more
europepmc +1 more source
This work unravels a novel function of CD103+ T cells in eradicating oxidative‐stressed somatic cells to prevent lung tumorigenesis and identifies specific CD103+ T cell‐decline as a key feature in the aged lung. This comprehensive study highlights the contribution of immuno‐dysregulation to the high incidence of aging‐associated lung cancers ...
Yu Xu+7 more
wiley +1 more source
Development of a Noninvasive Genotyping-In-Thousands (GTseq) Panel for Long-Term Conservation of Western Great Lakes Gray Wolves (<i>Canis lupus</i>). [PDF]
Hervey SD+5 more
europepmc +1 more source
The waterlogging tolerance of allotetraploid Actinidia valvata is inherited from one of its diploid progenitors, which leads to subgenome expression dominance, mediated by complex mechanisms including altered chromatin accessibility and DNA methylation.
Xiaoli Hu+14 more
wiley +1 more source
Harnessing Genomics for Breeding <i>Lantana camara</i> L.: Genotyping and Ploidy Testing of Clonal Lines Through ddRADseq Applications. [PDF]
Betto A+4 more
europepmc +1 more source
Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu+7 more
wiley +1 more source
Using feedback in pooled experiments augmented with imputation for high genotyping accuracy at reduced cost. [PDF]
Clouard C, Nettelblad C.
europepmc +1 more source
EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen+12 more
wiley +1 more source
Standardization of a Molecular Technique for Human Papillomavirus Genotyping in a Public-Health Service. [PDF]
De Souza SS+5 more
europepmc +1 more source
Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong+11 more
wiley +1 more source