Genome-wide association study of agronomic traits in winter wheat (Triticum aestivum L.) using a custom SNP marker set. [PDF]
Bazhenov M +11 more
europepmc +1 more source
Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li +12 more
wiley +1 more source
SAGPEK: fast and flexible approach to identify genotypes of Sanger sequencing data. [PDF]
Wang J +12 more
europepmc +1 more source
Genotype × environment interactions [PDF]
openaire +4 more sources
Fitness of the Genotypes at the B Locus Determining the Blood Group of Chickens
Ikuo Okada, Kyuki Matsumoto
openalex +2 more sources
Deficiency of SCAMP5 Triggers Pancreatic β‐Cell Secretory Dysfunction and Apoptosis
This study demonstrates that hyperglycemia in diabetes activates ChREBP, which epigenetically represses SCAMP5 expression in pancreatic β‐cells. This SCAMP5 deficiency impairs insulin secretion by downregulating the calcium channel CaV1.2. Furthermore, reduced SCAMP5 triggers β‐cell apoptosis by stabilizing VDAC1 and enhancing its interaction with Bax,
Yingqi Zhang +10 more
wiley +1 more source
Combined SNP parental haplotyping and intensity analysis identifies meiotic and mitotic aneuploidies and frequent segmental aneuploidies in preimplantation human embryos. [PDF]
Handyside AH +7 more
europepmc +1 more source
Researchers have identified a citrus chimera with distinctive tissue origins and carotenoid profiles. It is discovered that fruit tissues develop from all three cell layers but in different proportions. A key transcription factor, MYB107, regulates β‐cryptoxanthin production by directly activating carotenoid biosynthesis genes, explaining why some ...
Chi Zhang +8 more
wiley +1 more source
Development and validation of a high-density 'Amahysnp' genotyping array in grain amaranth (Amaranthus hypochondriacus). [PDF]
Singh R +12 more
europepmc +1 more source
This study reveals that Arabidopsis telomere repeat binding proteins (TRBs) form two closely related complexes. These complexes mediate H3K4me3 demethylation and transcriptional repression through a positive feedback loop and cooperate with PEAT and PRC2 complexes to regulate multiple histone modifications and gene expression across the genome ...
Qi Wang +7 more
wiley +1 more source

