Results 231 to 240 of about 1,163,135 (344)

Hosts and Commensal Bacteria Synergistically Antagonize Opportunistic Pathogens at the Single‐Cell Resolution

Advanced Science, EarlyView.
In the tripartite‐species model, Drosophila larvae stimulate lactate production through excreting digestion enzymes. S. marcescens population senses a cue of lactate and tends to diverge into virulent and reduced virulence subclusters with remarkable heterogeneity to metabolize carbon metabolism and counter colonization resistance, giving a fitness ...
Sheng Zhang, Ziguang Wang, Anqi Liu, Jinshu Li, Jingjing Zhuang, Xiaowen Ji, Paul I. Mulama, Maoye Li, Haiqun Cao, Eng‐King Tan, Wei Liu   +10 more
wiley   +1 more source

Sustainability in the laboratory: evaluating the reusability of microtitre plates for PCR and fragment detection. [PDF]

R Soc Open Sci
Berthelsen AL, Paijmans AJ, Forcada J, Hoffman JI.   +3 more
europepmc   +1 more source

Restriction site‐associated DNA sequencing, genotyping error estimation and de novo assembly optimization for population genetic inference

Molecular Ecology Resources, 2015
Alicia Mastretta‐Yanes, N. Arrigo, N. Alvarez, T. H. Jorgensen, D. Piñero, B. Emerson, B. Emerson   +6 more
semanticscholar   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

Next-generation sequencing-based tools or nanopore-based tools: which is more suitable for short tandem repeats genotyping of nanopore sequencing? [PDF]

Bioinform Adv
Han W, Zhang X, Zhang Q, Zhou Z.
europepmc   +1 more source

Influence of Genotype and Environment on Senescence in Peas, Pisum sativum L. [PDF]

, 1968
G. A. Marx
openalex   +1 more source

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

Advanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian, Chenghong Hu, Yong Xu, Wentao Xu, Zhe Wang, Wan Gan, Weiyang Tang, Lijiang Huang, Aleksandr V. Samorodov, Yi Wang   +9 more
wiley   +1 more source

The Evolutionary Trajectory and Prognostic Value of GITR+ Tregs Reprogramed by Tumor‐Intrinsic PD‐1/c‐MET Signaling in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), tumor‐intrinsic PD‐1 signaling activates the MET pathway, leading to the establishment of an immunosuppressive tumor microenvironment (TME). This MET‐driven signaling cascade promotes the selective accumulation of GITR+ regulatory T cells (Tregs), a highly immunosuppressive subset.
Jiande Han, Hanlin Yin, Taochen He, Junyi He, Zhenlai Jiang, Qiangda Chen, Zhihang Xu, Yuqi Xie, Yaolin Xu, Haibo Wang, Wenquan Wang, Wenchuan Wu, Yun Jin, Wenhui Lou, Jun Yu, Ning Pu, Liang Liu   +16 more
wiley   +1 more source

Corrigendum: A Larger Chocolate Chip—Development of a 15K Theobroma cacao L. SNP Array to Create High-Density Linkage Maps

Frontiers in Plant Science, 2018
Donald Livingstone III, Conrad Stack, Guiliana M. Mustiga, Dayana C. Rodezno, Carmen Suarez, Carmen Suarez, Freddy Amores, Freddy Amores, Frank A. Feltus, Keithanne Mockaitis, Omar E. Cornejo, Juan C. Motamayor   +11 more
doaj   +1 more source

Multiplex amplicon sequencing for the comprehensive genotyping of <i>Mycoplasma pneumoniae</i>. [PDF]

Microbiol Spectr
Kubota H, Okuno R, Kenri T, Uchitani Y, Ariyoshi T, Yoshida I, Kobayashi K, Mitobe M, Suzuki J, Sadamasu K.   +9 more
europepmc   +1 more source