Results 111 to 120 of about 3,598 (226)

Oxidative Treatment for Reducing Persistent Populations of Escherichia coli Under Amoxicillin and Gentamicin Pressure. [PDF]

J Biophotonics
Correa BC, Pereira MVS, Bagnato VS, Blanco KC.   +3 more
europepmc   +1 more source

Carriage of antimicrobial‐resistant E. coli in urban stray cats (Felis catus)

Australian Veterinary Journal, EarlyView.
Antimicrobial resistance (AMR) in Escherichia coli is a growing concern in both human and veterinary medicine, driven by the inappropriate use of antimicrobials. Companion animals may act as community reservoirs and sentinels for antimicrobial‐resistant bacteria due to their close contact with humans and other animals.
JS Kuan, S Mukerji, D Hampson, S Abraham
wiley   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source

Unveiling the molecular mechanisms of burn injury through integrated single-cell and bulk transcriptomic analysis. [PDF]

PLoS One
Zhu X, Huang N, Pan Y, Le X, Cui S, Li J, Fan Y.   +6 more
europepmc   +1 more source

The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, restores blood–brain barrier integrity in a human stem cell‐based model of ischaemic stroke

British Journal of Pharmacology, EarlyView.
Ischaemic stroke is characterised by acute cerebrovascular occlusion and blood–brain barrier (BBB) breakdown. Our results indicated that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) ameliorated the loss of BBB integrity, changed the morphology of brain endothelial cells, increased the level of basement membrane and ...
Anikó Szecskó, Koppány Párdi, Zuhao Cui, Gergő Porkoláb, Zsófia Hoyk, Csilla Kovács, Janet F. Adegbite, Virág Fodor, Nárcisz M. Cser, László Dér, Krisztina Nagy, Csilla Sajben, Roland Tengölics, Mária A. Deli, Szilvia Veszelka   +14 more
wiley   +1 more source

Nanostructured Lipid Carriers Co-Loaded with Doxycycline, Gentamicin, and Thymol for Enhanced Intracellular Antibacterial Activity Against <i>Brucella melitensis</i>. [PDF]

Int J Nanomedicine
Morovati Moez N, Arabestani MR, Taheri M, Karami P, Alikhani MY, Kazemi S, Hosseini SM.   +6 more
europepmc   +1 more source

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

Cell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo, Xiaoya Zhang, Danmei Zhang, Chunxia Shi, Luwen Wang, Zuojiong Gong   +5 more
wiley   +1 more source

Genedrive kit for detecting single nucleotide polymorphism m.1555A>G in neonates and their mothers: a systematic review and cost-effectiveness analysis.

Health Technol Assess
Shabaninejad H, Kenny RP, Robinson T, Stoniute A, O'Keefe H, Still M, Thornton C, Pearson F, Beyer F, Meader N.   +9 more
europepmc   +1 more source

The newly identified <i>grdA</i> gene confers high-level plazomicin resistance in <i>Salmonella enterica</i> serovars. [PDF]

Antimicrob Agents Chemother
Hikal AF, Zhao S, Foley S, Khan AA.
europepmc   +1 more source

Pronounced Reductions in Plasma Citrulline Indicate Severe Intestinal Mucosal Barrier Injury During Induction Therapy for Pediatric Acute Myeloid Leukemia

European Journal of Haematology, EarlyView.
ABSTRACT Objectives Pediatric acute myeloid leukemia (AML) chemotherapy regimens are frequently burdened by fever episodes, systemic inflammation and bloodstream infections (BSI). Mucosal barrier injury may contribute to these complications, but its role in childhood AML remains uninvestigated.
Carla Warley Kjær, Maria Ebbesen Sørum, Silvia De Pietri, Claus Moser, Malene Johanne Petersen, Marianne Hoffmann, Henrik Hasle, Sarah Weischendorff, Klaus Müller   +8 more
wiley   +1 more source