Results 171 to 180 of about 3,588 (226)
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Annals of Internal Medicine, 1978
For a decade gentamicin has been used extensively because of its antimicrobial efficacy and the relatively low prevalence of clinical toxicity. Recently the more frequent appearance of resistant organisms, reports of increased nephrotoxicity and ototoxicity, and the development of newer aminoglycoside antibiotics have raised doubts about the continued ...
G B, Appel, H C, Neu
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For a decade gentamicin has been used extensively because of its antimicrobial efficacy and the relatively low prevalence of clinical toxicity. Recently the more frequent appearance of resistant organisms, reports of increased nephrotoxicity and ototoxicity, and the development of newer aminoglycoside antibiotics have raised doubts about the continued ...
G B, Appel, H C, Neu
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Journal of Infectious Diseases, 1969
gentamicin treatment. The majority of these patients were known already at the time of the first gentamicin symposium [2-5]. Of these patients, 8 had hearing disturbances of varying degree, 10 had complete loss of vestibular function, 1 had slight vestibular disturbance, and 6 had doubtful vestibular disorders that were reversible.
J, Wersäll +2 more
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gentamicin treatment. The majority of these patients were known already at the time of the first gentamicin symposium [2-5]. Of these patients, 8 had hearing disturbances of varying degree, 10 had complete loss of vestibular function, 1 had slight vestibular disturbance, and 6 had doubtful vestibular disorders that were reversible.
J, Wersäll +2 more
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Survey of Ophthalmology, 1976
Gentamicin, widely used in the treatment of ocular infections, is discussed in terms of its chemical structure, effectiveness against various organisms, and pharmacology. Dosages and methods of administration are detailed and toxic effects, reversible and irreversible, are noted.
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Gentamicin, widely used in the treatment of ocular infections, is discussed in terms of its chemical structure, effectiveness against various organisms, and pharmacology. Dosages and methods of administration are detailed and toxic effects, reversible and irreversible, are noted.
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New England Journal of Medicine, 1971
Pseudomonas infections have been difficult to treat and distressingly common in hospitalized patients, especially those with impaired host defenses. Consequently, carbenicillin and gentamicin were welcome additions to the limited number of antipseudomonas antibiotics available.
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Pseudomonas infections have been difficult to treat and distressingly common in hospitalized patients, especially those with impaired host defenses. Consequently, carbenicillin and gentamicin were welcome additions to the limited number of antipseudomonas antibiotics available.
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Journal of Paediatrics and Child Health, 1980
Serum gentamlcin assays were performed on 116 paired samples of sera from 99 infants, whose birthweights ranged from 740 g to 4400 g. The gentamicin levels obtained were then studied in relation to the dosage used, the time interval between doses and the birthweight.
A M, Finn, P J, Pemberton
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Serum gentamlcin assays were performed on 116 paired samples of sera from 99 infants, whose birthweights ranged from 740 g to 4400 g. The gentamicin levels obtained were then studied in relation to the dosage used, the time interval between doses and the birthweight.
A M, Finn, P J, Pemberton
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A Comparative Study of the Ototoxicity of Gentamicin and Gentamicin C1
Archives of Otolaryngology - Head and Neck Surgery, 1980Dose-response experiments comparing the ototoxic liability of the aminoglycoside antibiotics gentamicin sulfate and gentamicin C1 sulfate were conducted on guinea pigs. Measures of cochlear electrophysiology, histology, and the pharmacokinetic disposition of the drugs in the plasma and perilymph were made. Electrophysiological and histological measures
K E, Fox +3 more
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Gentamicin in Pediatrics. I. Report on Intrathecal Gentamicin
Journal of Infectious Diseases, 1971The results of the use of gentamicin in the treatment of meningitis or ventriculitis by both intrathecal and intramuscular routes are presented for 13 patients; these are in addition to the 12 reported previously. Levels of gentamicin in cerebrospinal fluid at intervals after an intraventricular dose of gentamicin indicate that adequate levels of the ...
R L, Newman, R J, Holt
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New England Journal of Medicine, 2003
To the Editor: Wilschanski et al. (Oct. 9 issue)1 report that full-length cystic fibrosis transmembrane conductance regulator (CFTR) protein was expressed more effectively on the surface of nasal epithelial cells after gentamicin treatment than after placebo in patients with cystic fibrosis who had premature stop codons. Bedwell et al.
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To the Editor: Wilschanski et al. (Oct. 9 issue)1 report that full-length cystic fibrosis transmembrane conductance regulator (CFTR) protein was expressed more effectively on the surface of nasal epithelial cells after gentamicin treatment than after placebo in patients with cystic fibrosis who had premature stop codons. Bedwell et al.
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