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Multi-Target Intervention of Traditional Chinese Medicine in Metabolic Dysfunction-Associated Steatohepatitis: Comprehensive Treatment Strategies from Lipotoxicity to Immune Regulation. [PDF]

Int J Gen Med
Deng Z, Wang Y, Niu S, Li Q, Shi T, Ma M, Wang Y.   +6 more
europepmc   +1 more source

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Chemical constituents ofGentiana macrophyllaPall.

Natural Product Research, 2010
A novel dimeric secoiridoid glucoside, gentimacroside (1), and six known compounds (2-7) were isolated from the roots of Gentiana macrophylla Pall. Their structures were established on the basis of spectroscopic analysis, especially by means of 1D-, 2D-NMR and HRESIMS analyses.
Zhi-Bo, Jiang, Hong-Li, Liu, Xiao-Qing, Liu, Ji-Ning, Shang, Jia-Rui, Zhao, Cheng-Shan, Yuan   +5 more
openaire   +2 more sources

Quality regionalization study on Gentianae Macrophyllae Radix

China Journal of Chinese Materia Medica, 2016
The 79 samples of Gentianae Macrophyllae Radix were collected based on the distributed information by document literature. Based on sample information, and using the regression model of Gentianae Macrophyllae Radix index component and environmental factors, and combined with the prediction results of ecological suitability by MaxEnt and principal ...
You-Yuan, Lu, Xiao-Bo, Zhang, Yan-Mei, Yang, Xiao-Hui, Ma, Tian-Tian, Zhu, Xiao-Hui, Yu, Ling, Jin   +6 more
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Allometric Equation for Estimating the Aboveground Biomass of Gentiana Algida, Gentiana macrophylla in Mongolia

Mongolian Journal of Botany
The traditional method of calculating plant biomass involves harvesting plant yields and measuring the weight difference between wet and dry samples. However, this method can have negative consequences for rare and extremely rare species of plants. Therefore, we are studying the method of calculating biomass using measurements such as the diameter ...
Indree Tuvshintogtokh
exaly   +2 more sources

Chemical and Genetic Comparative Analysis of Gentiana crassicaulis and Gentiana macrophylla

Chemistry & Biodiversity, 2016
Gentiana crassicaulis Duthie ex Burk. and Gentiana macrophylla Pall. are two main sources of Radix Gentianae Macrophyllae (Qinjiao) available in markets, which has a wide range of anti‐inflammatory effects and has been extensively used for fighting rheumatoid arthritis.
Yaping, Wang, Bashir, Ahmad, Baozhong, Duan, Rui, Zeng, Linfang, Huang   +4 more
openaire   +2 more sources

Acyl secoiridoids and antifungal constituents from Gentiana macrophylla

Phytochemistry, 1996
LC-UV-mass spectrometry and bioassay co-directed fractionation of an aqueous acetone extract of the roots of Gentiana macrophylla gave three new chromene derivatives and two novel and six known secoiridoids, along with kurarinone, kushenol I, beta-sitosterol, stigmasterol, daucosterol, beta-sitosterol-3-O-gentiobioside, alpha-amyrin, oleanolic acid ...
Tan, R X, Wolfender, Jean-Luc, Zhang, L X, Ma, W G, Fuzzati, N, Marston, A, Hostettmann, K   +6 more
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Seven new chemical constituents from the roots of Gentiana macrophylla pall

Fitoterapia, 2020
Gentimilegenins A, B (1, 2), (6R, 8R)-6-hydroxy swerimuslactone A (3), (6R, 8S)-6-hydroxy swerimuslactone A (4), 4-hydroxy roburic acid methyl ester (5), (±) 3'-hydroxy gentioxepine (6), N-heptacosanoyl anthranilic acid (7a), N-nonacosanoyl anthranilic acid (7b), together with 40 known compounds were isolated from the roots of Gentiana macrophylla Pall.
Shu-Bing, Hou, Xin, Wang, Rong, Huang, Huan, Liu, Hai-Min, Hu, Wen-Yi, Hu, Si-Tong, Lv, Huan, Zhao, Guang, Chen   +8 more
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Gentiopicrin-producing endophytic fungus isolated from Gentiana macrophylla

Phytomedicine, 2009
Gentiana macrophylla is a traditional Chinese medicinal plant. Its dominant active constituents are secoiridoids, mainly gentiopicrin. The objective of this study was to determine whether endophytic fungi isolated from this plant produce the bioactive ingredient gentiopicrin.
Hong, Yin, Qiang, Zhao, Feng-Ming, Sun, Tai, An   +3 more
openaire   +2 more sources

An Insight Into the Genes Involved in Secoiridoid Biosynthesis in Gentiana macrophylla by RNA-Seq

Molecular Biology Reports, 2014
The dried root of Gentiana macrophylla is a well-known traditional Chinese herbal medicine for treating jaundice, hepatitis, and stomachic and choleretic ailments. However, natural sources are now in short supply. A lack of information about its genetic background has been a great hindrance to producing its active constituents via genetic engineering ...
Zhe-Zhi Wang, Langjun Cui
exaly   +3 more sources