Bellidifolin from Gentianella acuta (Michx.) Hulten protects H9c2 cells from hydrogen peroxide-induced injury via the PI3K-Akt signal pathway [PDF]
Toxicology Reports, 2022 Cardiovascular disease is the most common disease in the world and the first among the causes of human death. Its morbidity and mortality increase annually, but no effective treatment is available.
Siqi Li +7 more
doaj +2 more sources
Gentianella lutescens subsp. carpatica J. Holub.: Shoot Propagation In Vitro and Effect of Sucrose and Elicitors on Xanthones Production [PDF]
Plants, 2021 In vitro shoot culture of the endangered medicinal plant Gentianella lutescens was established from epicotyl explants cultured on MS basal medium with 0.2 mg L−1 6-benzylaminopurine (BA) and evaluated for xanthones content for the first time.
Dijana Krstić-Milošević +4 more
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Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD4 [PDF]
Cell Death Discovery, 2023 To date, there is no effective therapy for pathological cardiac hypertrophy, which can ultimately lead to heart failure. Bellidifolin (BEL) is an active xanthone component of Gentianella acuta (G. acuta) with a protective function for the heart. However,
Dingyan Zhou +10 more
doaj +2 more sources
Gentianella macrosperma, a new species of Gentianella (Gentianaceae) from Xinjiang, China [PDF]
PhytoKeys, 2019 Gentianella macrosperma Ma ex H.F. Cao, J.D. Ya & Q.R. Zhang, a new species of Gentianaceae from Xinjiang, Northwest China is described and illustrated. This new species is unique in having equal length of corolla lobe and corolla tube, nectaries
Hai-Feng Cao +8 more
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Can we learn from the ecology of the Bohemian gentian and save another closely related species of Gentianella? [PDF]
PLoS ONE, 2019 Bohemian gentian (Gentianella praecox subsp. bohemica) is an endemic taxon that occurs on the Czech Massif and together with the Sturmian gentian (Gentianella obtusifolia subsp.
Zdenka Křenová +3 more
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Gen-miR-5 derived from Gentianella acuta inhibits PFKP to prevent fibroblast activation and alleviate myocardial fibrosis [PDF]
Frontiers in PharmacologyIntroductionMyocardial fibrosis (MF) is a key pathological change in heart failure, and lactate a product of glycolysis, is an important component affecting the process of MF. miRNAs derived from Gentianella acuta (G.
Hongyao Ge +12 more
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Conservation Genomics for Threatened New Zealand Gentianella calcis (Gentianaceae) and Implications for Vulnerable Limestone Ecosystems [PDF]
Ecology and EvolutionIn New Zealand, limestone habitats are a naturally insular ecosystem, and obligate limestone taxa are extremely vulnerable to habitat degradation and destruction.
Robb W. Eastman‐Densem +4 more
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Biomass Allocation in Gentianella turkestanorum is Driven by Environmental Factors and Functional Traits [PDF]
PlantsExploring the elevation distribution characteristics, biomass allocation strategies, and the effects of elevation, soil factors, and functional traits on the biomass of Gentianella turkestanorum (Gand.) Holub is of great significance for the production ...
Qingzhen Sun +3 more
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Bioactive Constituents from the Whole Plants of Gentianella acuta (Michx.) Hulten
Molecules, 2017 As a Mongolian native medicine and Ewenki folk medicinal plant, Gentianella acuta has been widely used for the treatment of diarrhea, hepatitis, arrhythmia, and coronary heart disease.
Zhijuan Ding +7 more
exaly +3 more sources
Desmethylbellidifolin From Gentianella acuta Ameliorate TNBS-Induced Ulcerative Colitis Through Antispasmodic Effect and Anti-Inflammation [PDF]
Frontiers in Pharmacology, 2019 Desmethylbellidifolin (DMB) is a natural xanthone extracted from Gentianella acuta, which is used as the antidiarrhea drug in traditional Mongolian medicines. It remains unknown whether DMB can ameliorate ulcerative colitis (UC).
Yajuan Ni +9 more
doaj +2 more sources