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The determination and metabolism of gentisic acid.

open access: yesThe Journal of biological chemistry, 2004
S, ROSEMAN, A, DORFMAN
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A Physicochemical Study of Gentisic Acid

Journal of the American Pharmaceutical Association (Scientific ed.), 1952
Potentiometric titration of pure gentisic acid, in aqueous solution, indicates a pK1, corresponding to ionization of the carboxyl group, of 3.1; the pK2, corresponding to ionization of a phenolic group, is 10.2. With molybdophosphotungstate T. S., gentisic acid produces a green color even in acid solution, permitting quantitative determination of the ...
A, OSOL, L J, KLECKNER
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Decoding regioselective reaction mechanism of gentisic acid catalyzed by the gentisate 1,2-dioxygenase enzyme

Catalysis Science & Technology, 2022
Gentisate 1,2-dioxygenase (GDO), a ring-fission non-heme dioxygenase enzyme, displays a unique regioselective reaction of gentisic acid (GTQ) in the presence of molecular oxygen.
Rounak Nath   +2 more
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Determination of Sodium Gentisate by Chromatography and Fluorescence

Nature, 1951
THE determination of sodium gentisate (2 – 5 di-hydroxybenzoate) in urine is important because of the use of gentisate as a therapeutic in rheumatic fever, and the presence of sodium gentisate in urine after administration of sodium salicylate1.
L, NANNINGA, B, BINK
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The enzymic oxidation of gentisic acid

Biochimica et Biophysica Acta, 1959
Abstract A cell-free bacterial preparation is described which can oxidatively cleave gentisic acid to yield maleylpyruvic acid. In the presence of GSH this preparation can be made to catalyze the isomerization and hydrolysis of maleylpyruvate to yield fumaric and pyruvic acids. Other sulfhydryl-containing compounds cannot replace reduced glutathione.
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Fluorescence of gentisic acid

Analytica Chimica Acta, 1975
M S, Stallings, S G, Schulman
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