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The selection and introduction of disease resistance genes in livestock not only provide health benefits to animals but opportunities for breeders and farmers to meet the growing demand for high-quality meat and milk while reducing agriculture’s ...
A. Mark Cigan, Pieter W. Knap
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Responsible innovation as transformational entrepreneurship by disabled people
Responsible innovation (RI) has emerged as a powerful idea concerning the effective governance of science, technology and innovation. While much attention has been devoted to understanding and promoting RI within science and research policy addressing ...
Eva Kašperová, Audley Genus
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Using residual regressions to quantify and map signal leakage in genomic prediction
Background Most genomic prediction applications in animal breeding use genotypes with tens of thousands of single nucleotide polymorphisms (SNPs). However, modern sequencing technologies and imputation algorithms can generate ultra-high-density genotypes
Bruno D. Valente+5 more
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The Female Reproductive Tract Microbiota: Friends and Foe
We do not seem to be the only owner of our body; it houses a large population of microorganisms. Through countless years of coevolution, microbes and hosts have developed complex relationships.
Lokesh Kumar+6 more
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In the COVID-19 pandemic year 2021, several countries have implemented a vaccine certificate policy, the “Green Pass Policy” (GPP), to reduce virus spread and to allow safe relaxation of COVID-19 restrictions and reopening of social and economic ...
Immacolata Polvere+16 more
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Background Whole-genome sequence (WGS) data harbor causative variants that may not be present in standard single nucleotide polymorphism (SNP) chip data. The objective of this study was to investigate the impact of using preselected variants from WGS for
Sungbong Jang+7 more
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Genetic and phenotypic time trends of litter size, piglet mortality, and birth weight in pigs
IntroductionLitter size in pigs has increased steadily since 1990. Because of unfavorable genetic correlations with piglet mortality, breeding goals should include survival traits next to litter size.
Pieter W. Knap+7 more
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Background The coupling of appropriate sequencing strategies and imputation methods is critical for assembling large whole-genome sequence datasets from livestock populations for research and breeding. In this paper, we describe and validate the coupling
Roger Ros-Freixedes+6 more
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Sequence variation, evolutionary constraint, and selection at the CD163 gene in pigs
Background In this work, we investigated sequence variation, evolutionary constraint, and selection at the CD163 gene in pigs. A functional CD163 protein is required for infection by porcine reproductive and respiratory syndrome virus, which is a serious
Martin Johnsson+8 more
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CARD14/CARMA2 Signaling and its Role in Inflammatory Skin Disorders
CARMA proteins represent a family of scaffold molecules which play several crucial biological functions, including regulation of immune response and inflammation, tissue homeostasis, and modulation of G-Protein Coupled Receptor (GPCR) signaling.
Tiziana Zotti+9 more
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