Results 41 to 50 of about 2,047,763 (335)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Estimating genetic parameters of digital behavior traits and their relationship with production traits in purebred pigs

open access: yesGenetics Selection Evolution
Background With the introduction of digital phenotyping and high-throughput data, traits that were previously difficult or impossible to measure directly have become easily accessible, offering the opportunity to enhance the efficiency and rate of ...
Mary Kate Hollifield   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

The genus of curve, pants and flip graphs [PDF]

open access: yes, 2015
This article is about the graph genus of certain well studied graphs in surface theory: the curve, pants and flip graphs. We study both the genus of these graphs and the genus of their quotients by the mapping class group.
Parlier, Hugo, Petri, Bram
core  

Genus Ranges of Chord Diagrams

open access: yes, 2014
A chord diagram consists of a circle, called the backbone, with line segments, called chords, whose endpoints are attached to distinct points on the circle.
Jonathan Burns   +3 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

A near-optimal approximation algorithm for Asymmetric TSP on embedded graphs

open access: yes, 2013
We present a near-optimal polynomial-time approximation algorithm for the asymmetric traveling salesman problem for graphs of bounded orientable or non-orientable genus.
Erickson, Jeff, Sidiropoulos, Anastasios
core   +1 more source

Genu Recurvatum Syndrome [PDF]

open access: yesJournal of Orthopaedic & Sports Physical Therapy, 1998
Genu recurvatum is a common entity found in the clinic that my have negative consequence to knee structures. The purpose of this article is to review the anatomy, biomechanics, and clinical effects associated with genu recurvatum. Genu recurvatum is operationally defined as knee extension greater than 5 degrees.
J K, Loudon, H L, Goist, K L, Loudon
openaire   +2 more sources

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