Results 61 to 70 of about 1,261,920 (303)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

The Genus Melianthus .

open access: yesBothalia, 1927
No abstract ...
E. P. Phillips, Joan Meyer
openaire   +2 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Phenotyping for Genetic Improvement of Feed Efficiency in Fish: Lessons From Pig Breeding

open access: yesFrontiers in Genetics, 2018
Feed incurs most of the cost of aquaculture production, so feed efficiency (FE) improvement is of great importance. Our aim is to use work done in pigs to formulate a logical framework for assessing the most useful component traits influencing feed ...
Pieter W. Knap, Antti Kause
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

A revision of the genus Astatoreochromis (Teleostei, Cichlidae), East-Africa [PDF]

open access: yes, 2013
A taxonomic revision of the cichlid genus Astatoreochromis is presented. Eighteen meristic and 23 morphometric measurements were taken on 185 individuals, including type specimens.
Vreven, Emmanuel   +6 more
core   +1 more source

Evolution in the genus Arum: a comparative analysis of morpohological and genetic variation. [PDF]

open access: yes
Testing the correlation of morphological and genetic marker variation enables the investigation of evolutionary processes. Knowledge of evolutionary processes can be used to identify those morphological characters that could be used to produce ...
Porteous, Robert
core   +5 more sources

MAPKs signaling is obligatory for male reproductive function in a development-specific manner

open access: yesFrontiers in Reproductive Health
Mitogen-activated protein kinases (MAPKs) represent widely expressed and evolutionarily conserved proteins crucial for governing signaling pathways and playing essential roles in mammalian male reproductive processes.
Lokesh Kumar   +8 more
doaj   +1 more source

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