Results 271 to 280 of about 683,342 (322)

Multi-perspective analysis of skin microbiota in elderly eczema patients. [PDF]

open access: yesPLoS One
Dong D   +8 more
europepmc   +1 more source

Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease

open access: yesAdvanced Science, EarlyView.
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su   +12 more
wiley   +1 more source

VITAP: a high precision tool for DNA and RNA viral classification based on meta-omic data. [PDF]

open access: yesNat Commun
Zheng K   +6 more
europepmc   +1 more source

Overcoming Extreme Ammonia Inhibition on Methanogenesis by Artificially Constructing a Synergistically Community with Acidogenic Bacteria and Hydrogenotrophic Archaea

open access: yesAdvanced Science, EarlyView.
This study proposes a two‐step biological strategy to synergistically enhance the three stages of anaerobic digestion, ultimately eliminating the extreme ammonia inhibition and breaking through the inefficiency bottleneck of conventional biotechnology.
Heng Wu   +6 more
wiley   +1 more source

Soft Electronic Switches and Adaptive Logic Gates Based on Nanostructured Gold Networks

open access: yesAdvanced Electronic Materials, EarlyView.
Reconfigurable threshold logic gates and reversible switches are here demonstrated on a flexible and stretchable substrate, by exploiting the adaptability of the complex network composed of gold cluster‐assembled film embedded in the polymer matrix.
Giacomo Nadalini   +5 more
wiley   +1 more source

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