Results 281 to 290 of about 1,901,326 (324)

Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis

Advanced Science, EarlyView.
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves, Darius Lane, Adam Wahida, Md. Jakaria, Pawel Kalinowski, Adam Southon, Abdel Ali Belaidi, Teresa Samperi‐Esteve, Triet Phu Minh Nguyen, Peng Lei, Marcus Krueger, Stefan Mueller, Marcus Conrad, Puja Agarwal, Sue E Leurgans, Julie Schneider, Ashley I. Bush, Scott Ayton   +17 more
wiley   +1 more source

Divergence in the sow vaginal microbiota is associated with fertility. [PDF]

Reproduction
Fletcher L, Zhan X, Song Y, Li J.
europepmc   +1 more source

Neutrophil‐Mimicking Nanomedicine Eliminates Tumor Intracellular Bacteria and Enhances Chemotherapy on Liver Metastasis of Colorectal Cancer

Advanced Science, EarlyView.
Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu, Xu Zhao, Yong Li, Xiaoya Ma, Weifeng Yang, Jie Ma, Wanglin Li, Wei Yuan   +7 more
wiley   +1 more source

Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409‐Ube2k‐Foxp3 Axis in Regulatory T Cells

Advanced Science, EarlyView.
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie, Lijun Du, Yunkun Lu, Xiuliu Guo, Xinyuan Zhou, Yifan Tong, Bo Shen, Xin Yu, Feng Guo, Hong Yu   +9 more
wiley   +1 more source

Gut microbiota composition in early pregnancy as a diagnostic tool for gestational diabetes mellitus. [PDF]

Microbiol Spectr
Yao W, Wen R, Huang Z, Huang X, Chen K, Hu Y, Li Q, Zhu W, Ou D, Bai H.   +9 more
europepmc   +1 more source

The Genus Aspergillus

Medical Mycology Journal, 2011
openaire   +3 more sources

Implantable Ion‐Selective Organic Electrochemical Transistors Enable Continuous, Long‐Term, and In Vivo Plant Monitoring

Advanced Science, EarlyView.
This work explores ion‐selective organic electrochemical transistors for real‐time, long‐term potassium monitoring in the xylem sap of living trees. This bioelectronic approach provides new insights into plant physiology and has the potential to revolutionize forest, agricultural, and ecological monitoring for smarter, more sustainable plant management.
Sanggil Han, Dalila Pasquini, Mathias Sorieul, Miguel H. Boratto, Luke Gatecliff, Alan Dickson, Suhyeon Jang, Stephanie Davy, George G. Malliaras, Yi Chen   +9 more
wiley   +1 more source

Characteristics of gut microbiota in longevity populations in China and its relationship with healthy aging. [PDF]

Medicine (Baltimore)
Deng M, Chen W, Wang X.
europepmc   +1 more source

Kinetically Limited Growth of Dendritic Tin Oxide Thin Films: a Machine Learning Study beyond the Structure Zone Diagram

Advanced Science, EarlyView.
This work presents a critical evaluation of the empirical Thornton's structure zone diagram, a cornerstone in predicting thin film microstructure. Through transmission electron microscopy, we observe that Sn─O thin films form nanosized dendrites, which are not expected according to the structure zone diagram.
Denis Music, Xuelian Xiao, Rami Naser, Keke Chang, Grzegorz Sadowski, Pär A. T. Olsson   +5 more
wiley   +1 more source