Results 41 to 50 of about 1,991,563 (339)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Estimating genetic parameters of digital behavior traits and their relationship with production traits in purebred pigs

open access: yesGenetics Selection Evolution
Background With the introduction of digital phenotyping and high-throughput data, traits that were previously difficult or impossible to measure directly have become easily accessible, offering the opportunity to enhance the efficiency and rate of ...
Mary Kate Hollifield   +5 more
doaj   +1 more source

A Generic Approach to Searching for Jacobians

open access: yes, 2007
We consider the problem of finding cryptographically suitable Jacobians. By applying a probabilistic generic algorithm to compute the zeta functions of low genus curves drawn from an arbitrary family, we can search for Jacobians containing a large ...
Sutherland, Andrew V.
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

On the Genus Two Free Energies for Semisimple Frobenius Manifolds

open access: yes, 2012
We represent the genus two free energy of an arbitrary semisimple Frobenius manifold as a sum of contributions associated with dual graphs of certain stable algebraic curves of genus two plus the so-called "genus two G-function".
A. Takahashi   +20 more
core   +1 more source

A revision of the neotropical genus Anahi Martínez (Coleoptera: Scarabaeidae: Melolonthinae) with the description of two new species [PDF]

open access: yes, 2007
El género Anahi Martínez del sur del Neotrópico es comprensivamente revisado y ahora contiene tres especies: A. dentata Ocampo & Ruiz- Manzanos especie nueva, A. guaraniticus Martínez y A. oblivia Ocampo & Ruiz-Manzanos especie nueva. Las nuevas especies
Ocampo, Federico Carlos   +1 more
core   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

A near-optimal approximation algorithm for Asymmetric TSP on embedded graphs

open access: yes, 2013
We present a near-optimal polynomial-time approximation algorithm for the asymmetric traveling salesman problem for graphs of bounded orientable or non-orientable genus.
Erickson, Jeff, Sidiropoulos, Anastasios
core   +1 more source

Genu Recurvatum Syndrome [PDF]

open access: yesJournal of Orthopaedic & Sports Physical Therapy, 1998
Genu recurvatum is a common entity found in the clinic that my have negative consequence to knee structures. The purpose of this article is to review the anatomy, biomechanics, and clinical effects associated with genu recurvatum. Genu recurvatum is operationally defined as knee extension greater than 5 degrees.
J K, Loudon, H L, Goist, K L, Loudon
openaire   +2 more sources

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