Results 21 to 30 of about 363,358 (296)
Geo-Presentation and Geo-Reaction [PDF]
Botanical Gazette, 1920 1. The reducing sugars remain constant throughout stimulation and response. 2. The hydrolyzable sugars increase on the convex side at the expense of the polysaccharides as response takes place. 3. The total sugars are constant until beginning of response, when the sugars of the convex side become greater. 4. The osmotic pressure increases until visible
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Pricing Analysis in Geo/Geo/1 Queueing System [PDF]
Mathematical Problems in Engineering, 2015 This paper studies the equilibrium behavior of customers and optimal pricing strategies of servers in a Geo/Geo/1 queueing system. Two common pricing mechanisms are considered. The first one is called ex-post payment (EPP) scheme where the server collects tolls proportional to queue times, and the second one is called ex-ante payment (EAP) scheme where
Ma, Yan, Liu, Zaiming
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PON2 blockade overcomes dexamethasone resistance in acute lymphoblastic leukemia
Hematology, 2022 Objectives The high frequency of chemotherapy resistance is ultimately responsible for clinical relapse in acute lymphoblastic leukemia (ALL). Nevertheless, the molecular mechanism relevant to glucocorticoid (GC) resistance remains ambiguous.
Pei-Ye Hui +3 more
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International Journal of General Medicine, 2022 Xueru Chen,1,* Kai Gao,2,* Zijin Xiang,1 Yujun Zhang,1 Xiangdong Peng1 1Department of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, People’s Republic of China; 2Department of Gastrointestinal Surgery ...
Chen X, Gao K, Xiang Z, Zhang Y, Peng X
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
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Geo-Environmental Evaluation of Shewasoor Soil, Kirkuk/ NE Iraq [PDF]
Kirkuk Journal of Science, 2018 The present research aimed to evaluate contamination levels of soil by heavy metals. Eight sites were selected for the collection of soil samples. The soil samples analyzed for eight heavy metals namely As, Pb, Cd, Cr, Co, Cu, Ni, and Zn by using ICP-MS ...
Mustafa J. A. Ali, Omer S. I. Al-Tamimi
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FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
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