Results 71 to 80 of about 363,358 (296)

EDNRB inhibits the growth and migration of prostate cancer cells by activating the cGMP-PKG pathway

Open Medicine
Prostate cancer (PCa) represents a substantial global health concern and a prominent contributor to male cancer-related mortality. The aim of this study is to explore the role of B-type endothelin receptor (EDNRB) in PCa and evaluate its therapeutic ...
Li Xun, Liu Bide, Wang Shuheng, Dong Qiang, Li Jiuzhi   +4 more
doaj   +1 more source

miR-873 and miR-105-2 May Affect the Tumour Microenvironment and are Potential Biomarkers for Lung Adenocarcinoma

International Journal of General Medicine, 2022
Hao Zhang,1 Yan Liu,2 Zhihong Xu,1 Quan Chen1 1Department of Reproductive and Genetic Diseases, Deyang People’s Hospital, Deyang, Sichuan, People’s Republic of China; 2Department of Pharmacy, Deyang People’s Hospital, Deyang, Sichuan, People’s Republic ...
Zhang H, Liu Y, Xu Z, Chen Q
doaj  

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Bioinformatics Analysis and Validation Identify CDK1 and MAD2L1 as Prognostic Markers of Rhabdomyosarcoma

Cancer Management and Research, 2020
Suying Lu,1,2,* Chengtao Sun,3,* Huimou Chen,1,2,* Chao Zhang,1,4,* Wei Li,5 Liuhong Wu,1,2 Jia Zhu,1,2 Feifei Sun,1,2 Junting Huang,1,2 Juan Wang,1,2 Zijun Zhen,1,2 Ruiqing Cai,1,2 Xiaofei Sun,1,2 Yizhuo Zhang,1,2 Xing Zhang1,6 1State Key Laboratory of ...
Lu S, Sun C, Chen H, Zhang C, Li W, Wu L, Zhu J, Sun F, Huang J, Wang J, Zhen Z, Cai R, Sun X, Zhang Y, Zhang X   +14 more
doaj  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Think tanks and education. FAES neoliberalism in the LOMCE

Education Policy Analysis Archives, 2015
The article focuses attention on the discourses of the Spanish neoliberal think tank Foundation for Social Studies and Analysis (FAES) of the conservative Popular Party (PP).
Geo Saura
doaj   +1 more source

The Geo-Cultural and Geo-Linguistic Dimension of Media [PDF]

International Letters of Social and Humanistic Sciences, 2014
Besides the potential advancement of technology, the global and local communication is framing itself within bigger dimensions. The messages delivered by actual media means and the intensive exchange of experiences and ideas are conceived by the communication specialists as the most effective ways to configure the positions and therefore, are offering ...
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

A GEO-SPATIAL APPROACH TO ASSESS TREE OUTSIDE FORESTS (TOF) IN HARYANA STATE, INDIA [PDF]

, 2020
K. E. Mothi Kumar, Ritesh Kumar, Promila Bishnoi, Vikas Sihag, Ravikant Bishnoi, Seema Rani, Partibha Sindhu, Sarika Budhwar, Parmod Kalkal, Shashikant Sharma, Poonam Sharma, Ritu Sharma, Venkateshwar Pandey, Meenakshi Dahiya, Vedpriya Arya, T. P. Singh, Vinod Kumar   +16 more
openalex   +1 more source