Results 61 to 70 of about 628,123 (310)
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Shanghai Jiaotong Daxue xuebao. Yixue banObjective·To establish a prognostic model for the overall survival (OS) of hepatocellular carcinoma (HCC) based on mitochondrial genes and clinical information.Methods·The gene expression and the clinical data of 369 HCC patients and 50 controls with ...
Kedeerya Aishanjiang +4 more
doaj +1 more source
The DIGMAP geo-temporal web gazetteer service [PDF]
, 2009 This paper presents the DIGMAP geo-temporal Web gazetteer service, a system providing access to names of places, historical periods, and associated geo-temporal information.
Martins, Bruno +3 more
core +1 more source
, 2015 Voor vier gemeenten, verspreid door het land en met verschillende bodemtypen en verschillende soorten teelt, is een pilot opgezet: Mag het een onsje minder zijn?
Kluiving, S.J. (GEO-LOGICAL) +4 more
core +1 more source
GEO Mountains Workshop: Interdisciplinary Monitoring, Data, and Capacity Sharing across East Africa [PDF]
, 2023 The workshop was part of a series of regional engagements undertaken in 2023-24 by the Mountain Research Initiative (MRI) in its role co-leading the Global Network on Observation and Information in Mountain Environments (GEO Mountains) under the ...
Thornton, James
core +1 more source
GEO Mountains General Inventory v1.4
, 2022 Inventory of metadata and links to potentially useful datasets and other resources pertaining to mountains globally (mostly gridded or remotely sensed).
GEO Mountains (12211185)
core +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
, 2010 Gezien de verstoorde staat van de bovenste 1,5 tot 2,5 meter van de bodem kan de archeologische verwachting voor de Romeinse Tijd tot aan de Nieuw Tijd naar beneden toe bijgesteld worden tot een lage verwachting voor deze perioden.
GEO-LOGICAL
core +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source