Prognostic analysis and validation of diagnostic marker genes in patients with osteoporosis
BackgroundsAs a systemic skeletal dysfunction, osteoporosis (OP) is characterized by low bone mass and bone microarchitectural damage. The global incidences of OP are high.MethodsData were retrieved from databases like Gene Expression Omnibus (GEO ...
Xing Wang +9 more
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Emamectin benzoate (EMB) is one of the high-efficacious pesticide commonly used to control the ferocious economic crop pest S. exigua in the field. The results of S.
Yang Sun +9 more
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Background: Valvular heart disease (VHD) is a major precipitating factor of atrial fibrillation (AF) that contributes to decreased cardiac function, heart failure, and stroke.
Qiaoqiao Li +10 more
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Intracellular metabolites in marine microorganisms during an experiment evaluating microbial mortality [PDF]
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Longnecker, K., & Kujawinski, E. B.
Kujawinski, Elizabeth B. +1 more
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Maximal information component analysis: a novel non-linear network analysis method. [PDF]
BackgroundNetwork construction and analysis algorithms provide scientists with the ability to sift through high-throughput biological outputs, such as transcription microarrays, for small groups of genes (modules) that are relevant for further research ...
Bennett, Brian +5 more
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Identification Of key prognostic genes in ovarian cancer using WGCNA and LASSO analysis
Ovarian cancer (OC) is the fifth leading cause of death in females. This study aims to identify new prognostic genes of OC through bioinformatics analysis. Based on two datasets from the NCBI GEO public database, we constructed two WGCNA networks.
Zhong Yu, Ling Ouyang
doaj +1 more source
Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery. [PDF]
The dopaminergic hypothesis of schizophrenia (SZ) postulates that positive symptoms of SZ, in particular psychosis, are due to disturbed neurotransmission via the dopamine (DA) receptor D2 (DRD2).
Blondell, Lucy +8 more
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RNAseq Analyses Identify Tumor Necrosis Factor-Mediated Inflammation as a Major Abnormality in ALS Spinal Cord [PDF]
ALS is a rapidly progressive, devastating neurodegenerative illness of adults that produces disabling weakness and spasticity arising from death of lower and upper motor neurons.
A Al-Chalabi +99 more
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Identifying Potential Diagnostic Genes for Diabetic Nephropathy Based on Hypoxia and Immune Status
Changyan Li,1 Feng Su,1 Le Zhang,2 Fang Liu,3 Wenxing Fan,1 Zhen Li,4 JingYuan Ma1 1Department of Nephrology, the First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People’s Republic of China; 2Institute for Integrative ...
Li C +6 more
doaj
Network and biosignature analysis for the integration of transcriptomic and metabolomic data to characterize leaf senescence process in sunflower [PDF]
In recent years, high throughput technologies have led to an increase of datasets from omics disciplines allowing the understanding of the complex regulatory networks associated with biological processes.
Di Rienzo, Julio Alejandro +5 more
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