Results 1 to 10 of about 7,905,046 (163)
Scientific Reports, 2023 Alzheimer’s disease (AD) is the most prevalent dementia disorder globally, and there are still no effective interventions for slowing or stopping the underlying pathogenic mechanisms.
Yanting Zhang, Hisanori Kiryu
doaj +2 more sources
Statistical Approaches for Gene Selection, Hub Gene Identification and Module Interaction in Gene Co-Expression Network Analysis: An Application to Aluminum Stress in Soybean (Glycine max L.). [PDF]
PLoS ONE, 2017 Selection of informative genes is an important problem in gene expression studies. The small sample size and the large number of genes in gene expression data make the selection process complex.
Samarendra Das +4 more
doaj +2 more sources
IET Systems Biology, 2022 This study aims to discover the genetic modules that distinguish glioblastoma multiforme (GBM) from low‐grade glioma (LGG) and identify hub genes. A co‐expression network is constructed using the expression profiles of 28 GBM and LGG patients from the ...
Dongdong Lin, Wei Li, Nu Zhang, Ming Cai
doaj +2 more sources
Integrated multiplex network based approach for hub gene identification in oral cancer
Heliyon, 2021 Background: The incidence of Oral Cancer (OC) is high in Asian countries, which goes undetected at its early stage. The study of genetics, especially genetic networks holds great promise in this endeavor.
Tripti Swarnkar
exaly +2 more sources
Frontiers in Genetics, 2021 Tumor recurrence is one of the most important risk factors that can negatively affect the survival rate of colorectal cancer (CRC) patients. However, the key regulators dictating this process and their exact mechanisms are understudied.
Shengwei Liu +4 more
doaj +3 more sources
Applied Sciences, 2021 Breast cancer metastasis can have a fatal outcome, with the prediction of metastasis being critical for establishing effective treatment strategies.
Byung-Chul Kim +5 more
doaj +1 more source
Iranian journal of pharmaceutical research, 2023 Background Polycystic ovary syndrome (PCOS) affects women of reproductive age globally with an incidence rate of 5% - 26%. Growing evidence reports important roles for microRNAs (miRNAs) in the pathophysiology of granulosa cells (GCs) in PCOS. Objectives
Roozbeh Heidarzadehpilehrood +4 more
semanticscholar +1 more source
Frontiers in Immunology, 2023 Background COVID-19 and sepsis represent formidable public health challenges, characterized by incompletely elucidated molecular mechanisms. Elucidating the interplay between COVID-19 and sepsis, particularly in geriatric patients suffering from sepsis ...
Guojun Qian +9 more
semanticscholar +1 more source
Identification of PDK4 as Hub Gene for Diabetic Nephropathy Using Co-Expression Network Analysis
Kidney & Blood Pressure Research, 2023 Introduction: Diabetic nephropathy (DN) is related to type 1 and type 2 diabetes. They are the leading cause of end-stage renal disease, but the underling specific pathogenesis of DN is not yet clear. Our study was conducted to explore how DN changed the
Yuan-Yuan Han +4 more
semanticscholar +1 more source
Frontiers in Molecular Neuroscience, 2022 Vascular dementia (VaD) is considered to be the second most common form of dementia after Alzheimer’s disease, and no specific drugs have been approved for VaD treatment.
Jun Shu, Wenshi Wei, Li Zhang
doaj +1 more source