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Navigating the Landscape: A Comprehensive Review of Current Virus Databases
Viruses, 2023 Viruses are abundant and diverse entities that have important roles in public health, ecology, and agriculture. The identification and surveillance of viruses rely on an understanding of their genome organization, sequences, and replication strategy ...
Muriel Ritsch +3 more
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Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]
PeerJ, 2013 Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Piroon Jenjaroenpun +5 more
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Decoding cell-type contributions to the cfRNA transcriptomic landscape of liver cancer
Human Genomics, 2023 Background Liquid biopsy, particularly cell-free RNA (cfRNA), has emerged as a promising non-invasive diagnostic tool for various diseases, including cancer, due to its accessibility and the wealth of information it provides.
Aram Safrastyan +2 more
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Advances in Non-Coding RNA Sequencing
Non-Coding RNA, 2021 Non-coding RNAs (ncRNAs) comprise a set of abundant and functionally diverse RNA molecules. Since the discovery of the first ncRNA in the 1960s, ncRNAs have been shown to be involved in nearly all steps of the central dogma of molecular biology.
Julia Micheel +2 more
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The Role of Non-Coding RNAs in the Human Placenta
Cells, 2022 Non-coding RNAs (ncRNAs) play a central and regulatory role in almost all cells, organs, and species, which has been broadly recognized since the human ENCODE project and several other genome projects.
Milena Žarković +3 more
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BMC Genomics, 2023 Background Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also humans (via zoonotic ...
Konrad Sachse +7 more
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BMC Genomics, 2017 Background High-grade serous ovarian carcinoma (HG-SOC) is the dominant tumor histologic type in epithelial ovarian cancers, exhibiting highly aberrant microRNA expression profiles and diverse pathways that collectively determine the disease ...
Vladimir A. Kuznetsov +2 more
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Plant Methods, 2022 Background Copy number determination is one of the first steps in the characterization of transgenic plant lines. The classical approach to this, Southern blotting, is time-consuming, expensive and requires massive amounts of high-quality genomic DNA ...
Jonas De Saeger +6 more
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Pathogens, 2020 To identify genome-based features characteristic of the avian and human pathogen Chlamydia (C.) psittaci and related chlamydiae, we analyzed whole-genome sequences of 33 strains belonging to 12 species. Using a novel genome analysis tool termed Roary ILP
Martin Hölzer +9 more
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BMC Cancer, 2021 Background Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer (BC). Treatment options for TNBC patients are limited and further insights into disease aetiology are needed to develop better therapeutic approaches ...
Chiara Giacomelli +12 more
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