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A Molecular Biology Database Digest [PDF]
Computational Biology or Bioinformatics has been defined as the application of mathematical and Computer Science methods to solving problems in Molecular Biology that require large scale data, computation, and analysis [18].
Bry, François, Kröger, Peer
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Assessment of the influence of intrinsic environmental and geographical factors on the bacterial ecology of pit latrines [PDF]
Funding Information: This research received financial support from the Bill and Melinda Gates Foundation (grant number OPP52641). AWW and JP were supported by the Wellcome Trust [grant number 098051]. AWW and the Rowett Institute of Nutrition and Health,
Abdelahi, Faraji +10 more
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Metabolomics Bioinformatics Analysis
The basics of data processing are to convert the original data file into a representation to help easily access the characteristics of each observed ion. These characteristics include ion retention time and m/z time, as well as ion intensity measurements in each raw data file.
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Exploring the impact of primer length on efficient gene detection via high-throughput sequencing
Reverse transcription (RT) is a crucial step in most RNA analysis methods. Optimizing protocols for this initial stage is critical for effective target detection, particularly when working with limited input RNA.
Julia Micheel +3 more
doaj +1 more source
GBCdb: RNA expression landscapes and ncRNA–mRNA interactions in gallbladder carcinoma
Gallbladder carcinoma (GBC), an aggressive malignant tumor of the biliary system, is characterized by high cellular heterogeneity and poor prognosis. Fewer data have been reported in GBC than other common cancer types. Multi-omics data will contribute to
Li Guo +8 more
doaj +1 more source
mockrobiota: a Public Resource for Microbiome Bioinformatics Benchmarking. [PDF]
Mock communities are an important tool for validating, optimizing, and comparing bioinformatics methods for microbial community analysis. We present mockrobiota, a public resource for sharing, validating, and documenting mock community data resources ...
Arron Shiffer +10 more
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PCA and K-Means decipher genome
In this paper, we aim to give a tutorial for undergraduate students studying statistical methods and/or bioinformatics. The students will learn how data visualization can help in genomic sequence analysis.
A Zinovyev +8 more
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TFBSTools: an R/bioconductor package for transcription factor binding site analysis. [PDF]
Summary: The ability to efficiently investigate transcription factor binding sites (TFBSs) genome-wide is central to computational studies of gene regulation.
Lenhard, B, Tan, G
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Bioinformatics analysis The following analysis protocol describe Sequences processing and analysis section.
Rosangela Bevitori +6 more
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