Results 51 to 60 of about 640,321 (318)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Bioinformatics Analysis v1 [PDF]

, 2020
A plethora of biological processes like gene transcription, DNA replication, DNA recombination, and chromosome segregation are mediated through protein–DNA interactions. A powerful method for investigating proteins within a native chromatin environment in the cell is chromatin immunoprecipitation (ChIP).
Vasso Makrantoni, Daniel Robertson, Adele L. Marston   +2 more
openaire   +1 more source

BioRuby: Bioinformatics software for the Ruby programming language [PDF]

, 2010
The BioRuby software toolkit contains a comprehensive set of free development tools and libraries for bioinformatics and molecular biology, written in the Ruby programming language.
Aerts, Jan, Raoul Bonnal, Jan Aerts, Prins, Pjotr, Nakao, M., Bonnal, Raoul, Prins, P., Goto, Naohisa, Pjotr Prins, Nakao, Mitsuteru, Katayama, T., Mitsuteru Nakao, Toshiaki Katayama, Naohisa Goto, Prins, J.C.P., Aerts, J., Goto, N., Bonnal, R., Katayama, A., Katayama, Toshiaki   +19 more
core   +1 more source

Automatic, fast, hierarchical, and non-overlapping gating of flow cytometric data with flowEMMi v2

Computational and Structural Biotechnology Journal, 2022
Flow cytometry has become a powerful technology for studying microbial community dynamics and ecology. These dynamics are tracked over long periods of time based on two-parameter community fingerprints consisting of subsets of cell distributions with ...
Carmen Bruckmann, Susann Müller, Christian Höner zu Siederdissen   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The Bioinformatic and Expression Analysis of PSMD4 Gene

Hacettepe Journal of Biology and Chemistry, 2018
26S proteasome non-ATPase subunit 4 (PSMD4) that has a molecular weight of 41 kDa is included on chromosome 1 (1q21.3). PSMD4 protein is a subunit of the 19S regulatory region in the 26S proteasome. The proteasome breaks down proteins that are not needed or non-functional in the cell.
Türkoğlu, Sümeyye Aydoğan, Güler, Gizem, Köçkar, Feray   +2 more
openaire   +4 more sources

Overview of Random Forest Methodology and Practical Guidance with Emphasis on Computational Biology and Bioinformatics [PDF]

, 2012
The Random Forest (RF) algorithm by Leo Breiman has become a standard data analysis tool in bioinformatics. It has shown excellent performance in settings where the number of variables is much larger than the number of observations, can cope with ...
König, Inke R., Boulesteix, Anne-Laure, Kruppa, Jochen, Janitza, Silke   +3 more
core   +1 more source

Endogenous Bornavirus-like Elements in Bats: Evolutionary Insights from the Conserved Riboviral L-Gene in Microbats and Its Antisense Transcription in Myotis daubentonii

Viruses
Bats are ecologically diverse vertebrates characterized by their ability to host a wide range of viruses without apparent illness and the presence of numerous endogenous viral elements (EVEs).
Muriel Ritsch, Tom Eulenfeld, Kevin Lamkiewicz, Andreas Schoen, Friedemann Weber, Martin Hölzer, Manja Marz   +6 more
doaj   +1 more source

Renal Carcinoma Is Associated With Increased Risk of Coronavirus Infections

Frontiers in Molecular Biosciences, 2020
Background: The current COVID-19 pandemic has affected most severely people with old age, or with comorbidities like hypertension, diabetes mellitus, and cancer.
Satyendra C. Tripathi, Satyendra C. Tripathi, Vishwajit Deshmukh, Vishwajit Deshmukh, Chad J. Creighton, Ashlesh Patil, Ashlesh Patil   +6 more
doaj   +1 more source