Results 31 to 40 of about 1,076,718 (296)

Bioinformatics Databases: State of the Art and Research Perspectives [PDF]

, 2003
Bioinformatics or computational biology, i.e. the application of mathematical and computer science methods to solving problems in molecular biology that require large scale data, computation, and analysis, is a research area currently receiving a ...
Bry, François, Kröger, Peer
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Development of a novel and rapid phenotype-based screening method to assess rice seedling growth

Plant Methods, 2020
Background Rice (Oryza sativa) is one of the most important model crops in plant research. Despite its considerable advantages, (phenotypic) bioassays for rice are not as well developed as for Arabidopsis thaliana.
Lena Vlaminck, Chananchida Sang-Aram, Deborah Botterman, Christine Jewel C. Uy, Mary Kay Harper, Dirk Inzé, Godelieve Gheysen, Stephen Depuydt   +7 more
doaj   +1 more source

Assembling highly repetitive Xanthomonas TALomes using Oxford Nanopore sequencing

BMC Genomics, 2023
Background Most plant-pathogenic Xanthomonas bacteria harbor transcription activator-like effector (TALE) genes, which function as transcriptional activators of host plant genes and support infection.
Annett Erkes, René P. Grove, Milena Žarković, Sebastian Krautwurst, Ralf Koebnik, Richard D. Morgan, Geoffrey G. Wilson, Martin Hölzer, Manja Marz, Jens Boch, Jan Grau   +10 more
doaj   +1 more source

Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes. [PDF]

, 2017
Background: MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients and in combination with bioinformatics analysis to evaluate the utility
A Brazma, A Nan, A Okuhara, A Turchinovich, B Aryal, B Mayr, B Sharif, B Zhang, BM Bolstad, BM Kuhn, BM Mayr, C Beyer, C Chen, C Guay, C Taurino, CL Andersen, D Dlouha, D Iliopoulos, D Zhang, DT Felson, F Kostopoulou, FE Nicolas, G Dennis Jr, G Li, G Tardif, GD Miles, GR Sondag, GS Lien, H Causton, JB van Meurs, JD Storey, JD Storey, KC Vickers, L Qi, M Cross, M Parrizas, MB Goldring, MC Hochberg, MD Paraskevopoulou, MP Gantier, OF Laterza, Q Zhuo, R Gernapudi, RF Loeser, RI Gregory, S Kluzek, S Kumar, S Miyaki, T Thomou, TA Karlsen, VM Borgonio Cuadra, W Cleveland, WM Reichmann, X Chen, X Chen, X Tan, X Wang, Y Klipper-Aurbach, Y Zhang, YH Li   +59 more
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Network analysis of hepatocellular carcinoma liquid biopsies augmented by single-cell sequencing data

Frontiers in Genetics, 2022
Liquid biopsy, the analysis of body fluids, represents a promising approach for disease diagnosis and prognosis with minimal intervention. Sequencing cell-free RNA derived from liquid biopsies has been very promising for the diagnosis of several diseases.
Aram Safrastyan, Aram Safrastyan, Damian Wollny, Damian Wollny, Damian Wollny   +4 more
doaj   +1 more source

A comprehensive multi-omics analysis reveals molecular features associated with cancer via RNA cross-talks in the Notch signaling pathway

Computational and Structural Biotechnology Journal, 2022
The Notch signaling has an important role in multiple cellular processes and is related to carcinogenic process. To understand the potential molecular features of the crucial Notch pathway, a comprehensive multi-omics analysis is performed to explore its
Li Guo, Sunjing Li, Xiaoqiang Yan, Lulu Shen, Daoliang Xia, Yiqi Xiong, Yuyang Dou, Lan Mi, Yujie Ren, Yangyang Xiang, Dekang Ren, Jun Wang, Tingming Liang   +12 more
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Single nucleotide polymorphisms from Theobroma cacao expressed sequence tags associated with witches' broom disease in cacao [PDF]

, 2009
In order to increase the efficiency of cacao tree resistance to witches¿ broom disease, which is caused by Moniliophthora perniciosa (Tricholomataceae), we looked for molecular markers that could help in the selection of resistant cacao genotypes.
Carels, Nicolas, Cascardo, Julio Cezar M., Gaiotto, Fernanda Amato, Gesteira, Abelmon, Gramacho, Karina Peres, Lima, Leila S., Lopes, Uilson Vanderlei, Micheli, Fabienne, Novais, R., Pires, José Luis, Zaidan, Humberto A.   +10 more
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TRAPID : an efficient online tool for the functional and comparative analysis of de novo RNA-Seq transcriptomes [PDF]

, 2013
Transcriptome analysis through next-generation sequencing technologies allows the generation of detailed gene catalogs for non-model species, at the cost of new challenges with regards to computational requirements and bioinformatics expertise.
Deforce, Dieter, Proost, Sebastian, Van Bel, Michiel, Van de Peer, Yves, Van Neste, Christophe, Vandepoele, Klaas   +5 more
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BioWorkbench: A High-Performance Framework for Managing and Analyzing Bioinformatics Experiments [PDF]

, 2018
Advances in sequencing techniques have led to exponential growth in biological data, demanding the development of large-scale bioinformatics experiments.
Barbosa, Helio J. C., Foster, Ian, Gadelha Jr, Luiz M. R., Katz, Daniel S., Loss, Guilherme, Magalhães, Thiago, Mattoso, Marta, Mondelli, Maria Luiza, Ocaña, Kary, Vasconcelos, Ana Tereza R., Wilde, Michael   +10 more
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Lipidomics Bioinformatics Analysis

, 2023
Untargeted and targeted lipidomics are two categories of lipidomics that are often used in combination for the discovery and quantification of differential lipid molecules. Untargeted lipidomics uses LC-MS and GC-MS technologies to unbiasedly detect the dynamic changes of all lipid molecules before and after the stimulation or disturbance in cells ...
openaire   +1 more source